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3-Hydroxy-trans-7,8-dihydro-7,8-dihydroxy-benzo(a)pyrene, a metabolite of 3-hydroxybenzo(a)pyrene.

作者信息

Ribeiro O, Kirkby C A, Hirom P C, Millburn P

出版信息

Adv Exp Med Biol. 1986;197:833-42. doi: 10.1007/978-1-4684-5134-4_79.

DOI:10.1007/978-1-4684-5134-4_79
PMID:3490133
Abstract
摘要

相似文献

1
3-Hydroxy-trans-7,8-dihydro-7,8-dihydroxy-benzo(a)pyrene, a metabolite of 3-hydroxybenzo(a)pyrene.
Adv Exp Med Biol. 1986;197:833-42. doi: 10.1007/978-1-4684-5134-4_79.
2
Secondary metabolites of benzo[a]pyrene: 3-hydroxy-trans-7,8-dihydro-7,8-dihydroxybenzo[a]pyrene, a biliary metabolite of 3-hydroxybenzo[a]pyrene in the rat.苯并[a]芘的次级代谢产物:3-羟基-反式-7,8-二氢-7,8-二羟基苯并[a]芘,大鼠体内3-羟基苯并[a]芘的一种胆汁代谢产物。
Carcinogenesis. 1985 Oct;6(10):1507-11. doi: 10.1093/carcin/6.10.1507.
3
Fungal oxidation of benzo[a]pyrene and (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene. Evidence for the formation of a benzo[a]pyrene 7,8-diol-9,10-epoxide.苯并[a]芘和(±)-反式-7,8-二羟基-7,8-二氢苯并[a]芘的真菌氧化作用。苯并[a]芘7,8-二醇-9,10-环氧化物形成的证据。
J Biol Chem. 1980 Jun 10;255(11):5159-63.
4
Kinetic analysis of the metabolism of benzo(a)pyrene to phenols, dihydrodiols, and quinones by high-pressure chromatography compared to analysis by aryl hydrocarbon hydroxylase assay, and the effect of enzyme induction.通过高压色谱法对苯并(a)芘代谢为酚类、二氢二醇和醌类的动力学分析与通过芳烃羟化酶测定法的分析比较,以及酶诱导的影响。
Cancer Res. 1975 Dec;35(12):3642-50.
5
Synthesis of putative oxidized metabolites of 8-methylbenzo[a]pyrene.8-甲基苯并[a]芘假定氧化代谢产物的合成。
Carcinogenesis. 1983 Oct;4(10):1297-9. doi: 10.1093/carcin/4.10.1297.
6
Glutathione conjugation of benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide in the perfused rat liver.苯并[a]芘-7,8-二氢二醇和苯并[a]芘-7,8-二氢二醇-9,10-环氧化物在灌注大鼠肝脏中的谷胱甘肽结合反应
Chem Biol Interact. 1983 Apr-May;44(1-2):185-93. doi: 10.1016/0009-2797(83)90139-4.
7
On the effect of cellular nucleophiles on the binding of metabolites of 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene and 9-hydroxybenzo(a)pyrene to nuclear DNA.关于细胞亲核试剂对7,8 - 二羟基 - 7,8 - 二氢苯并(a)芘和9 - 羟基苯并(a)芘代谢产物与核DNA结合的影响
Carcinogenesis. 1980 May;1(5):407-18. doi: 10.1093/carcin/1.5.407.
8
In vivo formation and persistence of DNA adducts in mouse and rat skin exposed to (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene and (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.在暴露于(±)-反式-7,8-二羟基-7,8-二氢苯并[a]芘和(±)-7β,8α-二羟基-9α,10α-环氧-7,8,9,10-四氢苯并[a]芘的小鼠和大鼠皮肤中DNA加合物的体内形成和持久性。
Carcinogenesis. 1986 Sep;7(9):1553-60. doi: 10.1093/carcin/7.9.1553.
9
Formation of the 11,12-diol as a metabolite of benzo(a)pyrene by rat skin in vivo.
Biochem Biophys Res Commun. 1982 Apr 14;105(3):935-41. doi: 10.1016/0006-291x(82)91060-9.
10
Metabolic activation to a mutagen of 3-hydroxy-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene, a secondary metabolite of benzo[a]pyrene.苯并[a]芘的次级代谢产物3-羟基-反式-7,8-二羟基-7,8-二氢苯并[a]芘向诱变剂的代谢活化。
Carcinogenesis. 1987 Nov;8(11):1621-7. doi: 10.1093/carcin/8.11.1621.

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1
In vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols.多氯联苯醇对3-羟基苯并[a]芘体外抑制人肝脏及cDNA表达的磺基转移酶活性的作用
Environ Health Perspect. 2005 Jun;113(6):680-7. doi: 10.1289/ehp.7837.