Horváth Réka A, Sütő Zsófia, Cséke Balázs, Schranz Dániel, Darnai Gergely, Kovács Norbert, Janszky Imre, Janszky József
Department of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary.
Department of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary; MTA-PTE Clinical Neuroscience MRI Research Group. Hungary, Ifjúság u. 20., H-7624 Pécs, Hungary; Department of Behavioral Sciences, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary.
Seizure. 2022 Jan;94:136-141. doi: 10.1016/j.seizure.2021.11.013. Epub 2021 Dec 1.
Studies examining epilepsy as a COVID-related death risk have come to conflicting conclusions. Our aim was to assess the prevalence of epilepsy among COVID-related deaths in Hungary.
Each COVID-19 infection case is required to be reported on a daily basis to the National Public Health Center of Hungary. This online report includes the beginning and end of the infection, as well as information on comorbidities. Death during infection is regarded as COVID-related. The anonymized data of each deceased patient are published on an information website (www.koronavirus.gov.hu) and provides up-to-date information on each patient with the date of death, the patient's sex, age, and chronic illness.
There were 11,968 patients who died of COVID-19 in Hungary between 13 March 2020 and 23 January 2021. Among 11,686 patients with no missing values for comorbidities, 255 patients had epilepsy (2.2%). Epilepsy was much more common among those who died at a young age: 9.3% of those who died under the age of 50 had epilepsy, compared with only 1.3% in those over the age of 80. The younger an age group was, the higher was the prevalence of epilepsy.
Patients who died of COVID-19 under the age of 50 were 10 to 20 times more likely to have epilepsy than what would have been expected from epidemiological data. Our results highlight the need for increased protection of young people with epilepsy from COVID-19 infection and the development of a vaccination strategy accordingly.
关于癫痫作为与新冠相关的死亡风险的研究得出了相互矛盾的结论。我们的目的是评估匈牙利与新冠相关死亡病例中癫痫的患病率。
要求每天向匈牙利国家公共卫生中心报告每例新冠病毒感染病例。这份在线报告包括感染的开始和结束时间，以及合并症信息。感染期间的死亡被视为与新冠相关。每位已故患者的匿名数据在一个信息网站（www.koronavirus.gov.hu）上公布，并提供每位患者的最新信息，包括死亡日期、患者性别、年龄和慢性病情况。
2020年3月13日至2021年1月23日期间，匈牙利有11968名患者死于新冠病毒。在11686名无合并症缺失值的患者中，255名患者患有癫痫（2.2%）。癫痫在年轻时死亡的人群中更为常见：50岁以下死亡者中有9.3%患有癫痫，而80岁以上者中只有1.3%。年龄组越年轻，癫痫的患病率越高。
50岁以下死于新冠病毒的患者患癫痫的可能性比流行病学数据预期的高10至20倍。我们的结果凸显了加强对癫痫青年患者的新冠病毒感染防护以及相应制定疫苗接种策略的必要性。
