慢性肾脏病患者最佳冠状动脉血运重建的聚焦综述：肾脏病中的冠状动脉血运重建
A focused review on optimal coronary revascularisation in patients with chronic kidney disease: Coronary revascularisation in kidney disease.
作者信息
Djohan Andie H, Sia Ching-Hui, Loh Joshua Ping-Yun
机构信息
Department of Medicine, National University Health System, Singapore.
Department of Cardiology, National University Heart Centre Singapore, National University Health System, Singapore.
出版信息
AsiaIntervention. 2019 Feb;5(1):32-40. doi: 10.4244/AIJ-D-18-00015. Epub 2019 Feb 20.
Abstract
Concomitant chronic kidney disease (CKD) and coronary artery disease (CAD) is known to have poor outcomes. With a thorough literature review, we discuss the pathophysiological basis behind accelerated atherosclerosis in CKD, and the role of percutaneous coronary intervention (PCI) in these patients, focusing on drug-eluting stents, coronary artery bypass grafting, and adverse outcomes. We discuss factors contributing to poor outcomes in these patients, and the need for more work in this subgroup.
摘要
已知慢性肾脏病（CKD）和冠状动脉疾病（CAD）并存时预后较差。通过全面的文献综述，我们讨论了CKD中动脉粥样硬化加速的病理生理基础，以及经皮冠状动脉介入治疗（PCI）在这些患者中的作用，重点关注药物洗脱支架、冠状动脉旁路移植术和不良结局。我们讨论了导致这些患者预后不良的因素，以及在这一亚组中开展更多研究工作的必要性。
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