Jiao Yu, Zhang Xiaogang, Xu Boyong, Li Guoqing, Cao Li
Department of Joint Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi Xinjiang, 830054, P.R.China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2021 Dec 15;35(12):1563-1573. doi: 10.7507/1002-1892.202104007.
To investigate the difference of total knee arthroplasty (TKA) with tantalum monoblock tibial component (TMT) and cemented tibial plateau prosthesis in patients of different ages.
The clinical data of 248 patients (392 knees) who underwent primary TKA between May 2014 and May 2019 and met the selection criteria were retrospectively analyzed. There were 54 males (98 knees) and 194 females (294 knees). Of the 122 patients (183 knees), less than 65 years old, 52 (75 knees, group A1) were treated with TMT and 70 (108 knees, group B1) were treated with cemented tibial plateau prosthesis; of the 126 patients (209 knees), more than 65 years old, 57 (82 knees, group A2) were treated with TMT and 69 (127 knees, group B2) were treated with cemented tibial plateau prosthesis. The baseline data of patients, perioperative indicators [hemoglobin (Hb), hematocrit (Hct), total blood loss, unilateral operation time], effectiveness evaluation indicators [Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, visual analogue scale (VAS) score, Knee Society Scoring System (KSS) score, active flexion and extension range of motion (ROM) of the knee joint], complications, and imaging indicators [tibial prosthesis varus angle (β angle), tibial prosthesis posterior slope angle (δ angle), tibio-femoral angle, occurrence of radiolucent line, prosthesis survival rate] were recorded and compared.
There was no significant difference in gender, age, height, weight, body mass index, Kellgren-Lawrence grading, the length of hospital stay, and follow-up time between groups A1, B1 and groups A2, B2 ( >0.05). The unilateral operation time in groups A1 and A2 was significantly shorter than that in the corresponding groups B1 and B2 ( <0.05). There was no significant difference in differences of pre- and post-operative Hb and Hct and total blood loss between groups A1, B1 and groups A2, B2 ( >0.05). There was no significant difference in preoperative effectiveness evaluation indicators between groups A1, B1 and groups A2, B2 ( >0.05). There were significant differences in the differences of pre- and post-operative WOMAC activity and pain scores, KSS function and pain scores, and VAS scores between groups A1 and B1 ( <0.05); there was no significant difference in WOMAC stiffness score and ROM ( >0.05). There was no significant difference in the above indicators between groups A2 and B2 ( >0.05). There was no significant difference in the incidence of complications (2.7% 6.5%, 3.7% 3.1%) and prosthesis survival rate (100% 97.2%, 100% 99.2%) between groups A1, B1 and groups A2, B2 ( >0.05). During follow-up, there was no significant difference in β angle, δ angle, and tibio-femoral angle between groups A1, B1 and groups A2, B2 ( >0.05). In the evaluation of knee X-ray radiolucent line, 2 knees of group A1 and 2 knees of group A2 had radiolucent line at prosthesis-bone interface immediately after operation, and the radiolucent line was gradually filled by new bone, without new radiolucent line. During follow-up, 1 knee of group B1 and 1 knee of group B2 had prosthesis-bone interface radiolucent line, without radiolucent line widening or prosthesis loosening.
TMT is recommended in patients less than 65 years old, and the two types of prostheses are available for patients nore than 65 years old. However, the long-term effectiveness of the two types of prosthesis in patients of different ages needs further follow-up.
探讨钽单块胫骨组件(TMT)全膝关节置换术(TKA)与骨水泥固定胫骨平台假体在不同年龄段患者中的差异。
回顾性分析2014年5月至2019年5月期间接受初次TKA且符合入选标准的248例患者(392膝)的临床资料。其中男性54例(98膝),女性194例(294膝)。122例(183膝)年龄小于65岁的患者中,52例(75膝,A1组)采用TMT治疗,70例(108膝,B1组)采用骨水泥固定胫骨平台假体治疗;126例(209膝)年龄大于65岁的患者中,57例(82膝,A2组)采用TMT治疗,69例(127膝,B2组)采用骨水泥固定胫骨平台假体治疗。记录并比较患者的基线数据、围手术期指标[血红蛋白(Hb)、红细胞压积(Hct)、总失血量、单侧手术时间]、疗效评估指标[西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分、视觉模拟量表(VAS)评分、膝关节协会评分系统(KSS)评分、膝关节主动屈伸活动度(ROM)]、并发症及影像学指标[胫骨假体内翻角(β角)、胫骨假体后倾坡度角(δ角)、胫股角、透亮线的发生情况、假体生存率]。
A1、B1组与A2、B2组在性别、年龄、身高、体重、体重指数、Kellgren-Lawrence分级、住院时间及随访时间方面差异均无统计学意义(>0.05)。A1组和A2组的单侧手术时间明显短于相应的B1组和B2组(<0.05)。A1、B1组与A2、B2组术前、术后Hb、Hct及总失血量差异均无统计学意义(>0.05)。A1、B1组与A2、B2组术前疗效评估指标差异均无统计学意义(>0.05)。A1组与B1组术后WOMAC活动度和疼痛评分、KSS功能和疼痛评分及VAS评分差异有统计学意义(<0.05);WOMAC僵硬评分及ROM差异无统计学意义(>0.05)。A2组与B2组上述指标差异均无统计学意义(>0.05)。A1、B1组与A2、B2组并发症发生率(2.7%对6.5%,3.7%对3.1%)及假体生存率(100%对97.2%,100%对99.2%)差异均无统计学意义(>0.05)。随访期间,A1、B1组与A2、B2组β角、δ角及胫股角差异均无统计学意义(>0.05)。在膝关节X线透亮线评估中,A1组2膝及A2组2膝术后即刻在假体-骨界面出现透亮线,随后透亮线逐渐被新生骨填充,未出现新的透亮线。随访期间,B1组1膝及B2组1膝假体-骨界面出现透亮线,未出现透亮线增宽或假体松动。
推荐65岁以下患者使用TMT,65岁以上患者两种假体均可选用。然而,两种假体在不同年龄段患者中的长期疗效仍需进一步随访。