State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China; Beijing Engineering Research Center of Advanced Elastomers, Beijing University of Chemical Technology, Beijing 100029, China.
State Key Laboratory of NBC Protection for Civilian, Research Institute of Chemical Defense, Academy of Military Sciences PLA China, Beijing 100191, China.
Int J Biol Macromol. 2022 Jan 15;195:449-455. doi: 10.1016/j.ijbiomac.2021.12.029. Epub 2021 Dec 14.
The antibacterial and barrier properties of natural rubber used as gloves are very important for the safety of medical staffs. In this research, the silver (Ag) particles were loaded on the surface of graphene oxide (GO) first modified by polydopamine (PDA). Then, the complex particles (Ag-PDA-GO) were introduced into the natural rubber (NR) latex, and the Ag-PDA-GO/NR film composites were obtained by the dipping method. Results showed that a fine dispersion of Ag-PDA-GO in NR film was obtained due to the isolation effect of Ag and PDA between GO sheets. Compared with those of pristine NR composite, when the GO content was only 0.2 phr, the tensile strength, tear strength and modulus at 100% and 300% strains of the composites increase by 66.7%, 128%, 37.7% and 30.7%, respectively, compared with the pure NR. The gas diffusion coefficient was reduced by 15.6% due to the strong interface interaction between GO and NR macromolecules. When the GO content was only 0.1 phr, the minimum inhibitory concentrations (MIC) of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were 16 and 32 μg/mL, respectively. These results are of great significance for improving the barrier and antibacterial properties of medical rubber products.
天然橡胶用作手套的抗菌和阻隔性能对于医护人员的安全非常重要。在这项研究中，首先将银（Ag）颗粒负载在经聚多巴胺（PDA）改性的氧化石墨烯（GO）表面上。然后，将复合颗粒（Ag-PDA-GO）引入天然橡胶（NR）胶乳中，通过浸渍法获得 Ag-PDA-GO/NR 薄膜复合材料。结果表明，由于 Ag 和 PDA 在 GO 片层之间的隔离作用，Ag-PDA-GO 在 NR 薄膜中得到了很好的分散。与纯 NR 复合材料相比，当 GO 含量仅为 0.2 phr 时，复合材料的拉伸强度、撕裂强度和 100%和 300%应变时的模量分别提高了 66.7%、128%、37.7%和 30.7%，而纯 NR 的拉伸强度、撕裂强度和模量分别提高了 66.7%、128%、37.7%和 30.7%。由于 GO 和 NR 大分子之间的强界面相互作用，气体扩散系数降低了 15.6%。当 GO 含量仅为 0.1 phr 时，大肠杆菌（E. coli）和金黄色葡萄球菌（S. aureus）的最低抑菌浓度（MIC）分别为 16 和 32μg/mL。这些结果对于提高医用橡胶制品的阻隔和抗菌性能具有重要意义。
