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新冠疫情第一波高峰和封锁对法国颈动脉狭窄介入治疗管理的影响。

Impact of the first COVID-19 pandemic peak and lockdown on the interventional management of carotid artery stenosis in France.

机构信息

Department of Cardiovascular and Thoracic Surgery, University Hospital of Dijon, Dijon, France.

Biostatistics and Bioinformatics (DIM), University Hospital of Dijon, Dijon, France.

出版信息

J Vasc Surg. 2022 May;75(5):1670-1678.e2. doi: 10.1016/j.jvs.2021.11.064. Epub 2021 Dec 15.

Abstract

OBJECTIVE

The aim of this study was to evaluate the impact of the COVID-19 pandemic on the trends of carotid revascularization (endarterectomy [CEA], transfemoral carotid artery stenting [TFCAS]) for symptomatic and asymptomatic carotid stenosis before, during, and after the end of the first lockdown in 2020 in France.

METHODS

Nationwide data were provided by the French National Hospital Discharge database (Programme de Médicalisation des Systèmes d'Information). We retrospectively analyzed patients admitted for CEA or TFCAS in all French public and private hospitals during a 9-month period (January-September) in 2017, 2018, 2019, and 2020. Procedures were identified using the French Common Classification of Medical Procedures. Stenoses were considered symptomatic in the presence of stroke and/or transient ischemic attack codes (according to the International Classification of Diseases-Tenth Revision) during the stay, and asymptomatic in the absence of these codes. Hospitalization rates in 2020 were compared with the rates in the same period in the 3 previous years.

RESULTS

Between January and September 2020, 12,546 patients were hospitalized for carotid artery surgery (CEA and TFCAS) in France. Compared with the 3 previous years, there was a decrease in hospitalization rates for asymptomatic (-68.9%) and symptomatic (-12.6%) CEA procedures in April, starting at the pandemic peak concomitant with the first national lockdown. This decrease was significant for asymptomatic CEA (P < .001). After the lockdown, while CEA for asymptomatic stenosis returned to usual activity, CEA for symptomatic stenosis presented a significant rebound, up 18.52% in August compared with previous years. Lockdown also had consequences on TFCAS procedures, with fewer interventions for both asymptomatic (-60.53%) and symptomatic stenosis (-16.67%) in April.

CONCLUSIONS

This study demonstrates a severe decrease for all interventions during the first peak of the COVID-19 pandemic in France. However, the trends in the postlockdown period were different for the various procedures. These data can be used to anticipate future decisions and organization for cardiovascular care.

摘要

目的

本研究旨在评估 2020 年法国首次封锁结束前后,COVID-19 大流行对症状性和无症状性颈动脉狭窄患者颈动脉血运重建(颈动脉内膜切除术[CEA]、经股动脉颈动脉支架置入术[TFCAS])趋势的影响。

方法

全国范围内的数据由法国国家住院数据库(Programme de Médicalisation des Systèmes d'Information)提供。我们回顾性分析了 2017 年、2018 年、2019 年和 2020 年 9 个月(1 月至 9 月)期间所有法国公立和私立医院因 CEA 或 TFCAS 而入院的患者。通过法国常用医疗程序分类法识别程序。根据国际疾病分类第十版,住院期间有中风和/或短暂性脑缺血发作代码(根据国际疾病分类第十版)的狭窄被认为是症状性的,没有这些代码的狭窄被认为是无症状性的。2020 年的住院率与前 3 年同期的住院率进行了比较。

结果

2020 年 1 月至 9 月期间,法国有 12546 名患者因颈动脉血管手术(CEA 和 TFCAS)住院。与前 3 年相比,4 月无症状(-68.9%)和症状性(-12.6%)CEA 手术的住院率下降,这与大流行高峰同时发生,也是首次全国封锁之时。无症状性 CEA 下降具有显著意义(P<.001)。封锁后,尽管无症状性狭窄的 CEA 恢复正常活动,但症状性狭窄的 CEA 呈现出显著的反弹,与前几年相比,8 月增加了 18.52%。封锁也对 TFCAS 手术产生了影响,4 月无症状(-60.53%)和症状性狭窄(-16.67%)的手术数量减少。

结论

本研究表明,法国 COVID-19 大流行的第一个高峰期间,所有干预措施都严重减少。然而,封锁后的趋势因各种程序而异。这些数据可用于预测未来心血管护理的决策和组织。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf5e/8684845/e313af778007/gr1_lrg.jpg

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