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斜方肌硬纤维瘤:一例报告。

Desmoid tumor of trapezius muscle: A case report.

作者信息

Harouachi Abdelhakim, Ramdani Abdelbassir, Kharkhach Ayoub, Akouh Nada, Bouhout Tariq, Bennani Amal, Serji Badr, Harroudi Tijani El

机构信息

Surgical Oncology Department, Regional Oncology Center, Mohammed VI University Hospital, Oujda, Morocco.

Mohammed First University Oujda, Faculty of Medicine and Pharmacy Oujda, Oujda, Morocco.

出版信息

Ann Med Surg (Lond). 2021 Dec 1;72:103127. doi: 10.1016/j.amsu.2021.103127. eCollection 2021 Dec.

Abstract

INTRODUCTION

Desmoid tumors are benign fibrous entities developed from connective tissue, and they result from muscle fascia or aponeurosis. Surgical excision is the main pillar of treatment.

CASE REPORT

A 29-year-old female patient presented with a left postero-lateral cervical swelling that had been evolving for 11 months. Cervical MRI showed a mass at the expense of the trapezium muscle measuring 41 × 68 × 81 mm. A biopsy of the mass was performed, concluding a desmoid tumor. The patient underwent a large resection of the tumor involving the left trapezius muscle. An immunohistochemistry staining was performed, demonstrating cytoplasmic labeling with anti AML antibody, and nuclear labeling of tumor cells with anti-beta-catenin antibody. The case was analyzed by a multidisciplinary committee, and it was decided to follow the patient for surveillance.

DISCUSSION

The localization of desmoid tumors in the trapezius muscle is extremely rare. The main risk of these benign lesions is infiltration of surrounding tissue leading to morbidity and mortality. Recurrence is a main feature of these tumors, even if complete excision has been performed. Unresectable desmoid tumors require medical and non-surgical treatment such as hormone therapy (tamoxifen), and chemotherapy with vinblastine and methotrexate.

CONCLUSION

Desmoid tumor of trapezius muscle is classified as benign without metastatic power, and the main risk is infiltration of surrounding tissue.

摘要

引言

硬纤维瘤是由结缔组织形成的良性纤维性肿物,起源于肌筋膜或腱膜。手术切除是主要的治疗方法。

病例报告

一名29岁女性患者,左侧颈后外侧肿物已持续发展11个月。颈部磁共振成像(MRI)显示以斜方肌为代价形成的肿物,大小为41×68×81毫米。对该肿物进行活检,结果为硬纤维瘤。患者接受了包括左侧斜方肌在内的肿物扩大切除术。进行了免疫组织化学染色,显示抗AML抗体的胞质标记以及抗β-连环蛋白抗体对肿瘤细胞的核标记。该病例由多学科委员会进行分析,决定对患者进行随访监测。

讨论

硬纤维瘤位于斜方肌极为罕见。这些良性病变的主要风险是周围组织浸润导致发病和死亡。复发是这些肿瘤的主要特征,即使已进行了完整切除。不可切除的硬纤维瘤需要药物和非手术治疗,如激素治疗(他莫昔芬)以及长春碱和甲氨蝶呤化疗。

结论

斜方肌硬纤维瘤被归类为无转移能力的良性肿瘤,主要风险是周围组织浸润。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1adf/8649079/2cbe1eac5f93/gr1.jpg

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