新型冠状病毒肺炎相关脑脓肿的病因：1例病例报告及文献复习
COVID-19-associated brain abscess caused by : A case report and review of literature.
作者信息
Samaddar Arghadip, Diwakar Jyoti, Krishnan Priya, Veena Kumari H B, Kavya M, Konar Subhas, Sharma Dinesh A, Nandeesh B N, Goyal Aditi, Nagarathna S
机构信息
Department of Neuromicrobiology, National Institute of Mental Health and Neuro Sciences, Bengaluru, 560029, Karnataka, India.
Department of Neurosurgery, National Institute of Mental Health and Neuro Sciences, Bengaluru, 560029, Karnataka, India.
出版信息
Med Mycol Case Rep. 2022 Mar;35:9-14. doi: 10.1016/j.mmcr.2021.12.002. Epub 2021 Dec 16.
We report the first case of Coronavirus Disease 2019 (COVID-19)-associated brain abscess caused by a rare species, . The patient was a known diabetic and had received systemic corticosteroids for the treatment of COVID-19. He underwent craniotomy and evacuation of abscess. The pus aspirate grew a basidiomycetous yeast, morphologically resembling species. The isolate was initially misidentified by VITEK® MS due to lack of mass spectral database of . Accurate identification was achieved by internal transcribed spacer-directed panfungal polymerase chain reaction. The patient had a favorable outcome following surgical intervention and antifungal therapy.
我们报告了首例由一种罕见物种引起的2019冠状病毒病（COVID-19）相关脑脓肿病例。该患者为已知糖尿病患者，曾接受全身性皮质类固醇治疗COVID-19。他接受了开颅手术并进行了脓肿引流。脓液抽吸物培养出一种担子菌酵母，形态上类似于该物种。由于缺乏该物种的质谱数据库，该分离株最初被VITEK® MS误鉴定。通过内转录间隔区定向的泛真菌聚合酶链反应实现了准确鉴定。患者在手术干预和抗真菌治疗后取得了良好的结果。
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