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单发和多发食管-胃肠道息肉中肿瘤的患病率:5 年回顾性组织病理学研究。

Prevalence of neoplasia in solitary and multiple esophago-gastrointestinal polyps: 5 years retrospective histopathological study.

机构信息

Department of Pathology and Forensic Pathology, College of Medicine, Sulaimani University, Kurdistan Region-Iraq.

出版信息

Cell Mol Biol (Noisy-le-grand). 2021 Nov 25;67(3):44-51. doi: 10.14715/cmb/2021.67.3.6.

DOI:10.14715/cmb/2021.67.3.6
PMID:34933734
Abstract

The increasing use of endoscopy has led to more discernable abnormalities in the stomach, including polyps. Gastric polyps encompass a spectrum of pathologic conditions that can vary in histology, neoplastic potential, and management. Despite their high prevalence, there is a paucity of literature to support management and treatment decisions for endoscopists. The goal of this review is to summarize clinical, endoscopic, and histopathologic features of various polyps, review syndromes associated with such polyps and provide management recommendations. The present study was carried out for analyzing and comparing the prevalence of neoplasia in polyps (Solitary and multiple) removed endoscopically from the esophagus, stomach, and bowel undergoing screening. Five years retrospective study was done on patients who underwent endoscopy procedures including Oesophagogastroduodenoscopy (OGD) and colonoscopy between June 2015 and March 2019 in Faruk Medical City Hospital, Sulaimani City. Age and sex of patients, site of occurrence, number of polyps (solitary or multiple), and polyps' histologic type of 369 cases were analyzed in this study. Regarding solitary polyps, out of 279 polyps, 155 were neoplastic (55%) and 124 were non-neoplastic polyps, while multiple polyps, out of a total of 90 cases, 68 were neoplastic (75%) and 22 were non-neoplastic. More than 78% of patients were above the age of 40 years. Tubular adenoma was the most commonly diagnosed polyp. Large bowel was the most commonly involved site and left-sided polyps outnumbered right-sided ones with the sigmoid colon being the most commonly involved site. Screening programs including endoscopy, especially the colon for detecting polyps and particularly the colorectal region can be helpful to reduce morbidity and mortality of patients.

摘要

内窥镜的使用越来越广泛,导致胃内可识别的异常情况包括息肉。胃息肉包括一系列病理状况,其在组织学、肿瘤潜能和管理方面可能有所不同。尽管胃息肉的发病率很高,但支持内镜医生进行管理和治疗决策的文献却很少。本综述的目的是总结各种息肉的临床、内镜和组织病理学特征,回顾与这些息肉相关的综合征,并提供管理建议。本研究旨在分析和比较在筛查期间经内镜切除的食管、胃和肠中的息肉(单发和多发)的肿瘤发生率。对 2015 年 6 月至 2019 年 3 月在苏莱曼尼亚法鲁克医疗城医院进行食管胃十二指肠镜(OGD)和结肠镜检查的患者进行了为期 5 年的回顾性研究。本研究分析了 369 例患者的年龄和性别、发病部位、息肉数量(单发或多发)和息肉的组织学类型。对于单发息肉,在 279 个息肉中,有 155 个为肿瘤性(55%),124 个为非肿瘤性息肉,而多发性息肉,在总共 90 例中,有 68 个为肿瘤性(75%),22 个为非肿瘤性。超过 78%的患者年龄在 40 岁以上。管状腺瘤是最常见的诊断息肉。大肠是最常受累的部位,左半结肠的息肉多于右半结肠,其中乙状结肠最常受累。包括内镜检查在内的筛查计划,特别是结肠镜检查,对于发现息肉,特别是结直肠区域的息肉,可以帮助降低患者的发病率和死亡率。

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Prevalence of neoplasia in solitary and multiple esophago-gastrointestinal polyps: 5 years retrospective histopathological study.单发和多发食管-胃肠道息肉中肿瘤的患病率:5 年回顾性组织病理学研究。
Cell Mol Biol (Noisy-le-grand). 2021 Nov 25;67(3):44-51. doi: 10.14715/cmb/2021.67.3.6.
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