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检测 SARS-CoV-2 感染的行为和阳性情况:来自荷兰基于网络的参与式监测的见解。

Testing behaviour and positivity for SARS-CoV-2 infection: insights from web-based participatory surveillance in the Netherlands.

机构信息

Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands

Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.

出版信息

BMJ Open. 2021 Dec 21;11(12):e056077. doi: 10.1136/bmjopen-2021-056077.

Abstract

OBJECTIVES

We aimed to identify populations at a high risk for SARS-CoV-2 infection but who are less likely to present for testing, by determining which sociodemographic and household factors are associated with a lower propensity to be tested and, if tested, with a higher risk of a positive test result.

DESIGN AND SETTING

Internet-based participatory surveillance data from the general population of the Netherlands.

PARTICIPANTS

Weekly survey data collected over a 5-month period (17 November 2020 to 18 April 2021) from a total of 12 026 participants who had contributed at least 2 weekly surveys was analysed.

METHODS

Multivariable analyses using generalised estimating equations for binomial outcomes were conducted to estimate the adjusted ORs of testing and of test positivity associated with participant and household characteristics.

RESULTS

Male sex (adjusted OR for testing (OR): 0.92; adjusted OR for positivity (OR): 1.30, age groups<20 (OR: 0.89; OR: 1.27), 50-64 years (OR: 0.94; OR: 1.06) and 65+ years (OR: 0.78; OR: 1.24), diabetics (OR: 0.97; OR: 1.06) and sales/administrative employees (OR: 0.93; OR: 1.90) were distinguished as lower test propensity/higher test positivity factors.

CONCLUSIONS

The factors identified using this approach can help identify potential target groups for improving communication and encouraging testing among those with symptoms, and thus increase the effectiveness of testing, which is essential for the response to the COVID-19 pandemic and for public health strategies in the longer term.

摘要

目的

通过确定哪些社会人口和家庭因素与检测意愿较低以及检测呈阳性的风险较高相关,来确定哪些人群感染 SARS-CoV-2 的风险较高,但不太可能接受检测,从而确定感染 SARS-CoV-2 风险较高但不太可能接受检测的人群。

设计和设置

基于互联网的荷兰普通人群参与性监测数据。

参与者

对总共 12026 名参与者在 5 个月期间(2020 年 11 月 17 日至 2021 年 4 月 18 日)每周收集的调查数据进行了分析,这些参与者至少提供了 2 份周度调查数据。

方法

使用二项式结果的广义估计方程进行多变量分析,以估计与参与者和家庭特征相关的检测和检测阳性的调整比值比(OR)。

结果

男性(检测的调整 OR(OR):0.92;阳性的调整 OR(OR):1.30)、年龄组<20 岁(OR:0.89;OR:1.27)、50-64 岁(OR:0.94;OR:1.06)和 65 岁以上(OR:0.78;OR:1.24)、糖尿病患者(OR:0.97;OR:1.06)和销售/行政人员(OR:0.93;OR:1.90)为检测意愿较低/检测阳性较高的因素。

结论

使用这种方法确定的因素可以帮助确定具有症状的人群中提高沟通和鼓励检测的潜在目标人群,从而提高检测的有效性,这对 COVID-19 大流行的应对和长期公共卫生策略至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8675/8692782/a4dca4d9a28d/bmjopen-2021-056077f01.jpg

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