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归国旅行者发热:一例类鼻疽病例及文献综述

Fever in a returning traveler: A case and literature review of melioidosis.

作者信息

Arya Akanksha, Shaikh Hamadullah, Weber Devin, Pettengill Matthew, Moss Sean

机构信息

Thomas Jefferson University Hospital, 111 S 11th St, Philadelphia, PA 19107, United States.

出版信息

IDCases. 2021 Nov 23;26:e01340. doi: 10.1016/j.idcr.2021.e01340. eCollection 2021.

Abstract

is an aerobic, motile, non-spore-forming gram-negative bacillus found in tropical endemic environments that causes the disease melioidosis. Melioidosis displays a diversity of clinical presentations ranging from septic shock to chronic latent infection, often with characteristic abscesses in multiple organs. Melioidosis is an opportunistic infection, with risk factors, including diabetes, alcohol use, chronic lung disease, and chronic renal disease, and these risk factors increase the severity of disease (Wiersinga et al., 2006) [1]. In this case report, we illustrate a case of a 32 year old man with several risk factors and recent travel to an endemic region presenting with melioidosis. Our case demonstrates the challenges in obtaining a diagnosis in a non-endemic location, highlights a complex presentation of this disease, and describes the multifaceted clinical management required to care for this patient. As global travel increases, there is an increased need for clinician awareness of this disease in non-endemic regions.

摘要

是一种需氧、可运动、不形成芽孢的革兰氏阴性杆菌,存在于热带流行环境中,可引起类鼻疽病。类鼻疽病临床表现多样,从感染性休克到慢性潜伏感染不等,常伴有多个器官出现特征性脓肿。类鼻疽病是一种机会性感染,危险因素包括糖尿病、饮酒、慢性肺病和慢性肾病,这些危险因素会增加疾病的严重程度(Wiersinga等人,2006年)[1]。在本病例报告中,我们阐述了一名32岁男性的病例,该患者有多种危险因素且近期前往流行地区,表现出类鼻疽病症状。我们的病例展示了在非流行地区进行诊断所面临的挑战,突出了该疾病复杂的临床表现,并描述了护理该患者所需的多方面临床管理。随着全球旅行增加,非流行地区的临床医生对这种疾病的认识需求也日益增加。

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本文引用的文献

4
Melioidosis.类鼻疽病。
Nat Rev Dis Primers. 2018 Feb 1;4:17107. doi: 10.1038/nrdp.2017.107.
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Outcomes of patients with melioidosis treated with meropenem.用美罗培南治疗类鼻疽患者的结果。
Antimicrob Agents Chemother. 2004 May;48(5):1763-5. doi: 10.1128/AAC.48.5.1763-1765.2004.

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