Guo Richard F, Wong Frances L, Perez Mario L
Department of Internal Medicine, Kaiser Permanente Medical Center , Fontana, CA, USA.
Department of Inpatient Pharmacy, Kaiser Permanente Medical Center , Fontana, CA, USA.
Infect Dis Rep. 2015 Mar 3;7(1):5791. doi: 10.4081/idr.2015.5791. eCollection 2015 Feb 24.
Burkholderia, an aerobic gram-negative rod, is the causative organism behind melioidosis and is a common soil and water organism found predominantly in South-East Asia. We report the case of a 68 year-old man returning from an extended trip to the Philippines, with splenic hypodense lesions on abdominal computer tomography scan, later confirmed to be culture-positive for Burkholderia pseudomallei. The patient was treated with a course of intravenous ceftazidime followed by eradication therapy with oral doxycycline and trimethoprim-sulfamethoxazole. He recovered with complete resolution of symptoms at follow up. In a returning traveler from an endemic area, melioidosis should be considered as part of the differential for any febrile illness with abscesses.
伯克霍尔德菌是一种需氧革兰氏阴性杆菌,是类鼻疽病的致病微生物,是一种常见于土壤和水中的微生物,主要分布在东南亚地区。我们报告了一例68岁男性病例,该患者从菲律宾长途旅行归来,腹部计算机断层扫描显示脾脏低密度病变,后来经证实为类鼻疽伯克霍尔德菌培养阳性。患者接受了一个疗程的静脉注射头孢他啶治疗,随后采用口服多西环素和甲氧苄啶-磺胺甲恶唑进行根除治疗。随访时患者症状完全缓解,已康复。对于来自流行地区的归国旅行者,类鼻疽病应被视为任何伴有脓肿的发热性疾病鉴别诊断的一部分。