Schneider Stefan, Junghaenel Doerte U, Zelinski Elizabeth M, Meijer Erik, Stone Arthur A, Langa Kenneth M, Kapteyn Arie
Dornsife Center for Self-Report Science & Center for Economic and Social Research University of Southern California Los Angeles California USA.
Leonard Davis School of Gerontology University of Southern California Los Angeles California USA.
Alzheimers Dement (Amst). 2021 Dec 8;13(1):e12252. doi: 10.1002/dad2.12252. eCollection 2021.
We investigate whether indices of subtle reporting mistakes derived from responses in self-report surveys are associated with dementia risk.
We examined 13,831 participants without dementia from the prospective, population-based Health and Retirement Study (mean age 69 ± 10 years, 59% women). Participants' response patterns in 21 questionnaires were analyzed to identify implausible responses (multivariate outliers), incompatible responses (Guttman errors), acquiescent responses, random errors, and the proportion of skipped questions. Subsequent incident dementia was determined over up to 10 years of follow-up.
During follow-up, 2074 participants developed dementia and 3717 died. Each of the survey response indices was associated with future dementia risk controlling for confounders and accounting for death as a competing risk. Stronger associations were evident for participants who were younger and cognitively normal at baseline.
Mistakes in the completion of self-report surveys in longitudinal studies may be early indicators of dementia among middle-aged and older adults.
我们研究了自我报告调查中回答所产生的细微报告错误指标是否与痴呆风险相关。
我们对来自基于人群的前瞻性健康与退休研究的13831名无痴呆参与者进行了检查(平均年龄69±10岁,59%为女性)。分析了参与者在21份问卷中的回答模式,以识别不合理回答(多变量异常值)、不兼容回答(古特曼错误)、默认回答、随机错误以及跳过问题的比例。在长达10年的随访中确定随后发生的痴呆情况。
在随访期间,2074名参与者患上痴呆,3717人死亡。每个调查回答指标都与未来痴呆风险相关,在控制混杂因素并将死亡作为竞争风险进行考量后。对于基线时年轻且认知正常的参与者,关联更为明显。
纵向研究中自我报告调查完成过程中的错误可能是中老年人群痴呆的早期指标。