Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing China.
Expert Rev Med Devices. 2022 Jan;19(1):43-61. doi: 10.1080/17434440.2022.2020095. Epub 2022 Jan 13.
As an emerging neuromodulation therapy, transcutaneous auricular vagus nerve stimulation (taVNS) has been proven to be safe and effective for epilepsy, major depressive disorders, insomnia, glucose metabolic disorders, pain, stroke, post stroke rehabilitation, anxiety, fear, cognitive impairment, cardiovascular disorders, tinnitus, Prader-Willi Syndrome, and COVID-19.
Although the history of taVNS is only two decades, the devices carrying taVNS technique have been constantly updated. Especially in recent years, the development of taVNS devices has presented a new trend. To conclude, the development of taVNS devices has entered a new era, thus the update speed and quality of taVNS devices will be considerably improved in the future. This article reviewed the history and classification of taVNS devices.
The correlation between the effectiveness and stimulation parameters from taVNS devices still remains unclear. There is a lack of standard or harmonization among different taVNS devices. Strategies, including further comparative research and establishment of standard, have been recommended in this article to promote the future development of taVNS devices.
经证实，经皮耳迷走神经刺激（taVNS）作为一种新兴的神经调节疗法，在癫痫、重度抑郁症、失眠、葡萄糖代谢紊乱、疼痛、中风、中风后康复、焦虑、恐惧、认知障碍、心血管疾病、耳鸣、普拉德-威利综合征和 COVID-19 等疾病的治疗中是安全且有效的。
尽管 taVNS 的历史只有二十年，但携带 taVNS 技术的设备一直在不断更新。特别是近年来，taVNS 设备的发展呈现出新的趋势。总之，taVNS 设备的发展已经进入了一个新时代，因此，未来 taVNS 设备的更新速度和质量将得到极大提高。本文综述了 taVNS 设备的历史和分类。
taVNS 设备的有效性和刺激参数之间的相关性尚不清楚。不同的 taVNS 设备之间缺乏标准或协调。本文建议采取进一步的比较研究和建立标准等策略，以促进 taVNS 设备的未来发展。
