Rostron Zachary P J, Green Rodney A, Kingsley Michael, Zacharias Anita
Department of Pharmacy and Biomedical Sciences, College of Science, Health and Engineering, La Trobe University, Bendigo, VIC 3550, Australia.
Department of Exercise Sciences, Faculty of Science, University of Auckland, Auckland 1023, New Zealand.
Biology (Basel). 2021 Nov 30;10(12):1251. doi: 10.3390/biology10121251.
To determine the effect of exercise-based rehabilitation programs on hip and knee muscle function and size in people with hip osteoarthritis.
Seven databases were systematically searched in order to identify studies that assessed muscle function (strength or power) and size in people with hip osteoarthritis after exercise-based rehabilitation programs. Studies were screened for eligibility and assessed for quality of evidence using the GRADE approach. Data were pooled, and meta-analyses was completed on 7 of the 11 included studies.
Six studies reported hip and/or knee function outcomes, and two reported muscle volumes that could be included in meta-analyses. Meta-analyses were conducted for four strength measures (hip abduction, hip extension, hip flexion, and knee extension) and muscle size (quadriceps femoris volume). For hip abduction, there was a low certainty of evidence with a small important effect (effect size = 0.28, 95% CI = 0.01, 0.54) favouring high-intensity resistance interventions compared to control. There were no other comparisons or overall meta-analyses that identified benefits for hip or knee muscle function or size.
High-intensity resistance programs may increase hip abduction strength slightly when compared with a control group. No differences were identified in muscle function or size when comparing a high versus a low intensity group. It is unclear whether strength improvements identified in this review are associated with hypertrophy or other neuromuscular factors.
确定基于运动的康复计划对髋骨关节炎患者髋部和膝部肌肉功能及大小的影响。
系统检索七个数据库，以确定评估基于运动的康复计划后髋骨关节炎患者肌肉功能（力量或功率）和大小的研究。筛选研究的合格性，并使用GRADE方法评估证据质量。汇总数据，并对纳入的11项研究中的7项进行荟萃分析。
六项研究报告了髋部和/或膝部功能结果，两项报告了可纳入荟萃分析的肌肉体积。对四项力量指标（髋外展、髋伸展、髋屈曲和膝伸展）和肌肉大小（股四头肌体积）进行了荟萃分析。对于髋外展，与对照组相比，高强度阻力干预有小的重要效应（效应量=0.28，95%CI=0.01，0.54），但证据确定性低。没有其他比较或总体荟萃分析发现对髋部或膝部肌肉功能或大小有好处。
与对照组相比，高强度阻力计划可能会轻微增加髋外展力量。比较高强度组和低强度组时，未发现肌肉功能或大小有差异。尚不清楚本综述中确定的力量改善是否与肌肉肥大或其他神经肌肉因素有关。
