Joly Charles-Alexandre, Reynard Pierre, Hermann Ruben, Seldran Fabien, Gallego Stéphane, Idriss Samar, Thai-Van Hung
Institut de l'Audition, Institut Pasteur, Université de Paris, INSERM, 75012 Paris, France.
Université Claude Bernard Lyon 1, 69100 Villeurbanne, France.
J Clin Med. 2021 Dec 13;10(24):5819. doi: 10.3390/jcm10245819.
Broader intra-cochlear current spread (ICCS) implies higher cochlear implant (CI) channel interactions. This study aimed to investigate the relationship between ICCS and speech intelligibility in experienced CI users. Using voltage matrices collected for impedance measurements, an individual exponential spread coefficient (ESC) was computed. Speech audiometry was performed to determine the intelligibility at 40 dB Sound Pressure Level (SPL) and the 50% speech reception threshold: I40 and SRT50 respectively. Correlations between ESC and either I40 or SRT50 were assessed. A total of 36 adults (mean age: 50 years) with more than 11 months (mean: 34 months) of CI experience were included. In the 21 subjects for whom all electrodes were active, ESC was moderately correlated with both I40 (r = -0.557, = 0.009) and SRT50 (r = 0.569, = 0.007). The results indicate that speech perception performance is negatively affected by the ICCS. Estimates of current spread at the closest vicinity of CI electrodes and prior to any activation of auditory neurons are indispensable to better characterize the relationship between CI stimulation and auditory perception in cochlear implantees.
更广泛的耳蜗内电流扩散（ICCS）意味着更高的人工耳蜗（CI）通道相互作用。本研究旨在调查有经验的CI使用者中ICCS与言语可懂度之间的关系。利用为阻抗测量收集的电压矩阵，计算了个体指数扩散系数（ESC）。进行言语测听以确定在40分贝声压级（SPL）时的可懂度以及50%言语接受阈值：分别为I40和SRT50。评估了ESC与I40或SRT50之间的相关性。共纳入36名成年人（平均年龄：50岁），其CI使用经验超过11个月（平均：34个月）。在所有电极均活跃的21名受试者中，ESC与I40（r = -0.557，P = 0.009）和SRT50（r = 0.569，P = 0.007）均呈中度相关。结果表明，言语感知性能受到ICCS的负面影响。在CI电极最接近处且在听觉神经元任何激活之前的电流扩散估计对于更好地表征人工耳蜗植入者中CI刺激与听觉感知之间的关系是不可或缺的。
