Iwanaga Hideyuki, Ueno Takefumi, Oribe Naoya, Hashimoto Manabu, Nishimura Jun, Nakayama Naho, Haraguchi Nami, Tateishi Hiroshi, Kunitake Yutaka, Mizoguchi Yoshito, Monji Akira
Department of Psychiatry, National Hospital Organization, Hizen Psychiatric Medical Center, 160 Mitsu, Yoshinogari, Kanzaki, Saga 842-0192, Japan.
Division of Clinical Research, National Hospital Organization, Hizen Psychiatric Medical Center, 160 Mitsu, Yoshinogari, Kanzaki, Saga 842-0192, Japan.
J Pers Med. 2021 Dec 6;11(12):1315. doi: 10.3390/jpm11121315.
The results of quantitative electroencephalography (qEEG) studies on electroconvulsive therapy (ECT) have been inconsistent, and indicators of the efficacy of ECT have not been clearly identified. In this study, we examined whether qEEG could be used as an indicator of the effect of ECT by measuring it during the course of treatment. We analyzed qEEG data before and after acute-phase ECT in 18 patients with schizophrenia, mood disorders, and other psychiatric disorders. We processed the qEEG data and compared the spectral power between the data acquired before and after ECT. The spectral power increased significantly after ECT in the delta, theta, and alpha bands. There was a strong significant correlation between the increase in the spectral power of the alpha band after acute ECT and improvement in the Brief Psychiatric Rating Scale score. Our results suggest that an increase in the alpha-band spectral power may be useful as an objective indicator of the treatment effect of acute ECT.
关于电休克治疗(ECT)的定量脑电图(qEEG)研究结果并不一致,ECT疗效的指标尚未明确确定。在本研究中,我们通过在治疗过程中进行测量,检验了qEEG是否可作为ECT效果的指标。我们分析了18例精神分裂症、情绪障碍和其他精神疾病患者急性期ECT前后的qEEG数据。我们对qEEG数据进行了处理,并比较了ECT前后获取的数据之间的频谱功率。ECT后,δ、θ和α频段的频谱功率显著增加。急性ECT后α频段频谱功率的增加与简明精神病评定量表评分的改善之间存在强显著相关性。我们的结果表明,α频段频谱功率的增加可能作为急性ECT治疗效果的客观指标。