Department of Pharmaceutical Sciences, School of Pharmacy, University of California-Irvine, Irvine, CA 92697, USA.
Department of Developmental and Cell Biology, School of Biological Sciences, University of California-Irvine, Irvine, CA 92697, USA.
Molecules. 2021 Dec 10;26(24):7498. doi: 10.3390/molecules26247498.
extract (YHS) has been used for centuries across Asia for pain relief. The extract is made up of more than 160 compounds and has been identified as alkaloids, organic acids, volatile oils, amino acids, alcohols, and sugars. However, the most crucial biological active constituents of YHS are alkaloids; more than 80 have been isolated and identified. This review paper aims to provide a comprehensive review of the phytochemical and pharmacological effects of these alkaloids that have significant ties to analgesia.
延胡索（YHS）在亚洲被广泛使用了数个世纪，用于缓解疼痛。该提取物由 160 多种化合物组成，已被鉴定为生物碱、有机酸、挥发油、氨基酸、醇类和糖类。然而，YHS 中最重要的生物活性成分是生物碱；已经分离和鉴定出 80 多种生物碱。本文旨在对这些生物碱的植物化学和药理学作用进行全面综述，这些生物碱与镇痛有重要关系。
