Fontanesi G, Traina G C, Giancecchi F, Tartaglia I, Rotini R, Virgili B, Cadossi R, Ceccherelli G, Marino A A
Ital J Orthop Traumatol. 1986 Sep;12(3):371-85.
The purpose of the study was to evaluate the possibility of preventing delayed union in fractures by the use of low-frequency pulsing electromagnetic fields (PEMFs). The study was conducted in two parts, both with control groups. Fibular osteotomies in rats and diaphyseal fractures of the tibia in humans were treated with and without electrical stimulation (PEMF). The rats were sacrificed on the 8th and 23rd days respectively in order to evaluate the histological picture of the repair callus and its mechanical resistance. In the human subjects, the clinical and radiological follow-up took into account various factors known to affect the rate of union in the various fracture groups. The results obtained suggest that PEMF stimulation is capable of accelerating and modulating the physiological process of union by its favourable effect on osteogenesis.
本研究的目的是评估使用低频脉冲电磁场（PEMF）预防骨折延迟愈合的可能性。该研究分为两个部分，均设有对照组。对大鼠的腓骨截骨术以及人类的胫骨干骨折分别进行有或无电刺激（PEMF）的治疗。分别在第8天和第23天处死大鼠，以评估修复性骨痂的组织学图像及其力学强度。在人类受试者中，临床和影像学随访考虑了已知会影响不同骨折组愈合速度的各种因素。所获得的结果表明，PEMF刺激通过对骨生成产生有利影响，能够加速和调节愈合的生理过程。
