Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University College of Medicine, Anyang 14068, Korea.
Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14068, Korea.
Int J Environ Res Public Health. 2021 Dec 19;18(24):13368. doi: 10.3390/ijerph182413368.
The purpose of the present study was to analyze the associations between weight change and osteoporosis in Korean adults.
Data from the 2016 Korean Community Health Survey were analyzed. A total of 159,741 participants who were ≥40 years of age were included. The histories of osteoporosis were surveyed in two ways: 'osteoporosis for entire life' and 'current osteoporosis'. The participants were grouped into three categories for simplification as follows: 'Weight L&M' (Tried to lose weight or Tried to maintain weight), 'Weight gain' (Tried to gain weight), and 'Never tried'. Additionally, we analyzed their relationship with obesity using the BMI.
The adjusted ORs for 'osteoporosis for entire life' were 1.20 (95% confidence interval [CI] 1.13-1.27) in the Weight L&M group and 1.83 (95% CI 1.64-2.05) in the Weight gain group. The adjusted ORs for 'current osteoporosis' were 1.16 (95% CI 1.08-1.25) in the Weight L&M group and 1.77 (95% CI 1.54-2.02) in the Weight gain group.
Compared to the Never tried group, being in either the Weight L&M or Weight gain groups showed a significant impact on the possibility of osteoporosis.
本研究旨在分析韩国成年人体重变化与骨质疏松症之间的关联。
对 2016 年韩国社区健康调查的数据进行了分析。共纳入 159741 名年龄≥40 岁的参与者。通过两种方式调查骨质疏松症的病史：“终生骨质疏松症”和“当前骨质疏松症”。为简化起见，将参与者分为三组：“体重减轻或维持”（试图减肥或试图维持体重）、“体重增加”（试图增加体重）和“从未尝试过”。此外，我们还使用 BMI 分析了它们与肥胖的关系。
体重减轻或维持组“终生骨质疏松症”的调整后 OR 为 1.20（95%CI 1.13-1.27），体重增加组为 1.83（95%CI 1.64-2.05）。体重减轻或维持组“当前骨质疏松症”的调整后 OR 为 1.16（95%CI 1.08-1.25），体重增加组为 1.77（95%CI 1.54-2.02）。
与从未尝试过的组相比，体重减轻或维持组或体重增加组与骨质疏松症的可能性显著相关。
