Shen Liping, Pang Xuehong, Wang Jie, Duan Yifan, Xu Peipei, Wang Shuo, Zhao Wenhua, Yang Zhenyu
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100081, China.
Wei Sheng Yan Jiu. 2021 Nov;50(6):900-925. doi: 10.19813/j.cnki.weishengyanjiu.2021.06.005.
To explore the association between different timing of introducing complementary foods during infancy and the body composition of children aged 3-5 years.
The data was from National Nutrition and Health Systematic Survey for 0-18 Years Old Children in China. A face-to-face interview to caregivers of children was conducted to retrospectively collect timing of introducing complementary foods of children aged 3-5 years. The bioelectrical impedance analysis was used to measure the body composition of children by professionally trained investigators. The exposure variable of the study was the timing of introducing complementary foods(≤5 months old, 6 months old and ≥7 months old). The outcome variables were the fat-free mass, fat-free mass index, body fat mass, body fat mass index, and percentage of body fat. According to age stratification, a multivariate linear regression model was used to calculate the mean, mean difference and 95% CI after adjusting for potential confounders.
After adjusting for potential confounders, there were no statistically significant difference in body fat mass, body fat mass index, percentage of body fat and fat-free mass index among different groups of timing for introducing complementary foods for children aged 3-5 years old. For children aged 3-5 years, after adjusting for potential confounders, the difference of fat free mass was statistically significant among children with different timing for introducing of complementary foods(3 years old: 12.89 kg vs. 12.66 kg vs. 12.94 kg, F=4.42, P=0.013; 5 years old: 16.27 kg vs. 16.23 kg vs. 16.66 kg, F=5.40, P=0.005). The fat free mass of children aged 3 years was lower when introducing complementary foods during 6 months of age than at ≤5 months of age(mean difference=-0.23 kg(95% CI-0.45--0.02 kg)). The fat free mass of children aged 5 years was higher when introducing complementary foods at ≥7 months of age than at≤5 months of age(mean difference=0.39 kg(95% CI 0.08-0.70 kg)).
It is found that the association between timing for introducing complementary foods during infancy and the fat mass indicators of children aged 3 to 5 years was not statistically significant, and the association between timing for introducing complementary foods and fat-free mass may be inconsistent for different fat-free mass indicators.
探讨婴儿期不同辅食添加时间与3至5岁儿童身体成分之间的关联。
数据来自中国0至18岁儿童营养与健康状况系统调查。对3至5岁儿童的照料者进行面对面访谈，以回顾性收集儿童辅食添加时间。由经过专业培训的调查人员使用生物电阻抗分析法测量儿童的身体成分。研究的暴露变量为辅食添加时间（≤5个月、6个月和≥7个月）。结局变量为去脂体重、去脂体重指数、体脂肪量、体脂肪量指数和体脂百分比。根据年龄分层，采用多变量线性回归模型，在调整潜在混杂因素后计算均值、均值差异和95%置信区间。
调整潜在混杂因素后，3至5岁儿童不同辅食添加时间组之间的体脂肪量、体脂肪量指数、体脂百分比和去脂体重指数无统计学显著差异。对于3至5岁儿童，调整潜在混杂因素后，不同辅食添加时间的儿童去脂体重差异有统计学意义（3岁：12.89千克对12.66千克对12.94千克，F = 4.42，P = 0.013；5岁：16.27千克对16.23千克对16.66千克，F = 5.40，P = 0.005）。3岁儿童在6个月时添加辅食时的去脂体重低于≤5个月时添加辅食（均值差异=-0.23千克（95%置信区间-0.45至-0.02千克））。5岁儿童在≥7个月时添加辅食时的去脂体重高于≤5个月时添加辅食（均值差异=0.39千克（95%置信区间0.08至0.70千克））。
发现婴儿期辅食添加时间与3至5岁儿童的体脂肪指标之间的关联无统计学显著意义，且不同去脂体重指标下，辅食添加时间与去脂体重之间的关联可能不一致。
