University of Ottawa, Department of Psychiatry, Ontario, Canada; The Ottawa Hospital, Department of Mental Health, Ontario, Canada; University of Ottawa, Ottawa Hospital Research Institute (OHRI) Clinical Epidemiology Program, Ottawa Ontario; Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology& Neuroscience, King's College London, London, United Kingdom; Centre for Innovation in Mental Health-Developmental Lab, School of Psychology, University of Southampton, and NHS Trust, Southampton, United Kingdom.
Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology& Neuroscience, King's College London, London, United Kingdom; Universidad Católica, Department of Psychology, Montevideo, Uruguay.
J Affect Disord. 2022 Feb 15;299:393-407. doi: 10.1016/j.jad.2021.07.048. Epub 2021 Jul 19.
. High-quality comprehensive data on short-/long-term physical/mental health effects of the COVID-19 pandemic are needed.
. The Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) is an international, multi-language (n=30) project involving >230 investigators from 49 countries/territories/regions, endorsed by national/international professional associations. COH-FIT is a multi-wave, on-line anonymous, cross-sectional survey [wave 1: 04/2020 until the end of the pandemic, 12 months waves 2/3 starting 6/24 months threreafter] for adults, adolescents (14-17), and children (6-13), utilizing non-probability/snowball and representative sampling. COH-FIT aims to identify non-modifiable/modifiable risk factors/treatment targets to inform prevention/intervention programs to improve social/health outcomes in the general population/vulnerable subgrous during/after COVID-19. In adults, co-primary outcomes are change from pre-COVID-19 to intra-COVID-19 in well-being (WHO-5) and a composite psychopathology P-Score. Key secondary outcomes are a P-extended score, global mental and physical health. Secondary outcomes include health-service utilization/functioning, treatment adherence, functioning, symptoms/behaviors/emotions, substance use, violence, among others.
. Starting 04/26/2020, up to 14/07/2021 >151,000 people from 155 countries/territories/regions and six continents have participated. Representative samples of ≥1,000 adults have been collected in 15 countries. Overall, 43.0% had prior physical disorders, 16.3% had prior mental disorders, 26.5% were health care workers, 8.2% were aged ≥65 years, 19.3% were exposed to someone infected with COVID-19, 76.1% had been in quarantine, and 2.1% had been COVID 19-positive.
. Cross-sectional survey, preponderance of non-representative participants.
. Results from COH-FIT will comprehensively quantify the impact of COVID-19, seeking to identify high-risk groups in need for acute and long-term intervention, and inform evidence-based health policies/strategies during this/future pandemics.
需要高质量的综合数据来了解 COVID-19 大流行对短期和长期身心健康的影响。
合作研究感染期间的健康与功能（COH-FIT）是一个国际性、多语言（n=30）项目，涉及来自 49 个国家/地区/地区的 230 多名研究人员，得到了国家/国际专业协会的认可。COH-FIT 是一项多波、在线匿名、横断面调查[第 1 波：2020 年 4 月至大流行结束，第 6 个月开始的 12 个月内进行第 2/3 波]，针对成年人、青少年（14-17 岁）和儿童（6-13 岁），利用非概率/滚雪球和代表性抽样。COH-FIT 的目的是确定不可改变/可改变的风险因素/治疗靶点，为预防/干预计划提供信息，以改善大流行期间/之后普通人群/弱势群体的社会/健康结果。在成年人中，主要共同结局是从 COVID-19 前到 COVID-19 期间幸福感（WHO-5）和复合精神病理学 P 评分的变化。主要次要结局是 P 扩展评分、全球心理健康和身体健康。次要结局包括卫生服务利用/功能、治疗依从性、功能、症状/行为/情绪、物质使用、暴力等。
自 2020 年 4 月 26 日起，截至 2021 年 7 月 14 日，来自六大洲 155 个国家/地区的超过 151,000 人参加了该研究。在 15 个国家/地区收集了≥1,000 名成年人的代表性样本。总体而言，43.0%的人有先前的身体疾病，16.3%的人有先前的精神疾病，26.5%的人是卫生保健工作者，8.2%的人年龄≥65 岁，19.3%的人接触过感染 COVID-19 的人，76.1%的人接受过隔离，2.1%的人 COVID-19 呈阳性。
横断面调查，非代表性参与者居多。
COH-FIT 的结果将全面量化 COVID-19 的影响，旨在确定需要急性和长期干预的高风险人群，并为此次大流行或未来的大流行提供循证卫生政策/策略。
