Rohn R D
Pediatrics. 1987 May;79(5):745-7.
The purpose of this study was to determine the manner of breast nipple (papilla) development occurring during puberty in girls on a longitudinal basis and to compare this development to the established criteria of sexual maturation. Forty-six girls (19 white and 27 black) were followed for periods of 2 to 5 years (mean 2.67 years). In each, the nipple diameter was measured and the Tanner stage assessed. Minimal nipple development occurred from stages PH1 to PH3 (3.24 to 4.44 mm) and B1 to B3 (3.00 to 4.72 mm) or more than 1 year prior to menarche (3.75 mm). Significant growth occurred beyond stages PH3 (PH4 6.54 mm, PH5 8.98 mm) and B3 (B4 7.25 mm, B5 9.41 mm) and from less than 1 year prior to menarche to more than 1 year after menarche (5.92 mm for girls less than 1 year premenarche, 7.88 mm for girls in their first year after menarche, and 9.05 mm for girls more than 1 year beyond menarche). A more objective definition for breast stages B4 and B5, based upon nipple diameter, is now feasible. Thus, these data enhance the precision with which physiologic events occurring toward the close of puberty in girls can be studied.
本研究的目的是纵向确定女孩青春期乳房乳头（乳头）发育的方式，并将这种发育与既定的性成熟标准进行比较。46名女孩（19名白人，27名黑人）被随访了2至5年（平均2.67年）。对每名女孩测量乳头直径并评估坦纳分期。乳头最小发育发生在PH1至PH3期（3.24至4.44毫米）和B1至B3期（3.00至4.72毫米），或初潮前1年以上（3.75毫米）。显著生长发生在PH3期之后（PH4期6.54毫米，PH5期8.98毫米）和B3期之后（B4期7.25毫米，B5期9.41毫米），以及初潮前不到1年至初潮后1年以上（初潮前不到1年的女孩为5.92毫米，初潮后第1年的女孩为7.88毫米，初潮后1年以上的女孩为9.05毫米）。基于乳头直径对乳房B4和B5期进行更客观的定义现在是可行的。因此，这些数据提高了研究女孩青春期后期发生的生理事件的精确性。
