Department of Urology, Icahn School of Medicine at Mt Sinai, New York, NY.
The Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mt Sinai, New York, NY.
JSLS. 2021 Oct-Dec;25(4). doi: 10.4293/JSLS.2021.00062.
The da Vinci SP® Surgical System received U.S. Food and Drug Administration approval for urological procedures in 2018. Here, we describe the first experience performing single-port robot-assisted donor nephrectomy (RADN) using the da Vinci SP® surgical system, present 90-day clinical outcomes, and discuss tips for operative success.
Seven consecutive patients underwent single-port RADN at a single institution between September 1, 2020 and March 31, 2021. Surgery was performed through a single, 60 mm Pfannenstiel incision with a 12 mm periumbilical assistant port for suction and vascular stapling. Donor characteristics, operative details, 90-day donor clinical outcomes, and recipient renal function were retrospectively evaluated.
Four female and three male patients successfully underwent single-port RADN without conversion to standard multiport or open approach. Six cases were left-sided. Estimated blood loss for each procedure was ≤ 50 mL. Mean operative time, warm ischemia time, and extraction time were 218.3 minutes (standard deviation [SD]: 16.3 minutes), 5 minutes 4 seconds (SD: 56 seconds), and 3 minutes 37 seconds (SD: 38 seconds). Mean pre-operative creatinine and estimated glomerular filtration rate were 0.79 mg/dL and 107.3 mL/min/1.73m, respectively. At six week's follow up, they were 1.22 mg/dL and 66.1 mL/min/1.73m. Average pain score at 48 hours postoperatively was 1.7/10. There were no Clavien-Dindo grade ≥ III complications within 90 days. All recipients experienced immediate and sustained return of renal function post-transplant.
Single-port RADN is a technically feasible and safe procedure with the da Vinci SP® system and can confer acceptable functional and cosmetic outcomes. Future studies are needed to define long-term outcomes and compare with previously established techniques for donor nephrectomy.
达芬奇 SP®手术系统于 2018 年获得美国食品和药物管理局批准用于泌尿外科手术。在这里,我们描述了首例使用达芬奇 SP®手术系统进行单端口机器人辅助供肾切除术(RADN)的经验,介绍了 90 天的临床结果,并讨论了手术成功的技巧。
2020 年 9 月 1 日至 2021 年 3 月 31 日,在一家单机构连续对 7 例患者进行了单端口 RADN。手术通过一个 60mm 的脐部旁切口和一个 12mm 的脐部辅助端口进行,用于抽吸和血管吻合。回顾性评估供体特征、手术细节、90 天供体临床结果和受体肾功能。
4 例女性和 3 例男性患者成功地进行了单端口 RADN,没有转换为标准多孔或开放方法。6 例为左侧。每例手术的估计出血量均≤50ml。平均手术时间、热缺血时间和提取时间分别为 218.3 分钟(标准差[SD]:16.3 分钟)、5 分钟 4 秒(SD:56 秒)和 3 分钟 37 秒(SD:38 秒)。术前肌酐和估算肾小球滤过率分别为 0.79mg/dL 和 107.3mL/min/1.73m。在 6 周的随访时,分别为 1.22mg/dL 和 66.1mL/min/1.73m。术后 48 小时平均疼痛评分 1.7/10。90 天内无 Clavien-Dindo 分级≥III 级并发症。所有受者在移植后均立即恢复并持续恢复肾功能。
使用达芬奇 SP®系统进行单端口 RADN 是一种技术上可行且安全的方法,可以获得可接受的功能和美容结果。需要进一步的研究来定义长期结果,并与以前建立的供肾切除术技术进行比较。