Roohé Suzanna L, Gan Ivan M, van der Weerd Kim, Lopuhaä Boaz, Verdijk Robert M, Paridaens Dion
Department of Oculoplastic and Orbital Surgery, The Rotterdam Eye Hospital, Rotterdam, The Netherlands.
Department of Ophthalmology, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands.
Case Rep Ophthalmol. 2021 Oct 26;12(3):870-874. doi: 10.1159/000519953. eCollection 2021 Sep-Dec.
Orbital metastasis may be the initial manifestation of a malignancy of unknown origin. The primary locations of orbital metastasis are usually the lung, prostate, gastrointestinal tract, skin, kidney, eye, or thyroid gland. Metastasis of gastric carcinoma to an extraocular eye muscle is extremely rare. A solitary thickening in an extraocular eye muscle with no inflammatory features is suspect for a tumor. Symptoms such as diplopia, proptosis, ptosis, vision loss, or pain may be associated with an orbital malignancy. Our patient, a 67-year-old man known with radically resected prostate cancer, presented with complaints of vertigo with a tendency to fall, headache, and diplopia when looking to the right. As a coincidental finding, swelling of the rectus lateralis muscle of the left eye was observed on imaging. Extensive additional investigations showed that a gastric carcinoma with intraorbital and leptomeningeal metastasis was the cause. In conclusion, a solitary thickened extraocular eye muscle should be recognized in time and examined further.
眼眶转移瘤可能是原发部位不明的恶性肿瘤的首发表现。眼眶转移瘤的原发部位通常是肺、前列腺、胃肠道、皮肤、肾脏、眼或甲状腺。胃癌转移至眼外肌极为罕见。眼外肌出现孤立性增厚且无炎症表现时应怀疑肿瘤。复视、眼球突出、上睑下垂、视力丧失或疼痛等症状可能与眼眶恶性肿瘤有关。我们的患者是一名67岁男性,已知患有前列腺癌且已行根治性切除术,他出现眩晕伴跌倒倾向、头痛以及向右看时复视的症状。影像学检查偶然发现左眼外直肌肿胀。进一步的全面检查显示,病因是胃癌伴眼眶及软脑膜转移。总之,应及时识别眼外肌的孤立性增厚并进一步检查。