Alghamdi Yousef G, Rub Malik Abdul, Kumar Dileep, Asiri Abdullah M
Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
R Soc Open Sci. 2021 Dec 22;8(12):211527. doi: 10.1098/rsos.211527. eCollection 2021 Dec.
The effect of various media (aqueous, NaCl, urea (U) and thiourea (TU)) on the micellization and adsorption activity of varied mixtures of imipramine hydrochloride (IMP) and benzethonium chloride (BZCl) is investigated via tensiometry. In an aqueous medium, the interactions between IMP and BZCl are also evaluated using UV-visible and FTIR spectroscopy. The interaction between components increases with increased mole fraction ( ) of BZCl in the mixed system (IMP + BZCl). Different parameters, such as micellar and the mixed monolayer component composition, the interaction parameters of the solution and the interface, the activity coefficients of the components in solution and at the interface, and thermodynamic parameters, are computed using different proposed theoretical models (i.e. Clint, Motomura, Rubingh and Rosen). The values obtained for the pure components and mixtures (IMP + BZCl) of all the compositions are found to be less in NaCl than in the aqueous solution while found more in the presence of U or TU. TU is more effective in increasing the of the pure and mixed systems than U. The Gibbs free energy values of the studied pure and mixed systems are negative, showing the spontaneous nature of the reaction.
通过表面张力测定法研究了各种介质（水、氯化钠、尿素（U）和硫脲（TU））对盐酸丙咪嗪（IMP）和苄索氯铵（BZCl）不同混合物的胶束化和吸附活性的影响。在水介质中，还使用紫外可见光谱和傅里叶变换红外光谱评估了IMP和BZCl之间的相互作用。在混合体系（IMP + BZCl）中，随着BZCl摩尔分数（ ）的增加，各组分之间的相互作用增强。使用不同的理论模型（即克林特、本村、鲁宾和罗森模型）计算了不同参数，如胶束和混合单分子层的组分组成、溶液和界面的相互作用参数、溶液和界面中各组分的活度系数以及热力学参数。发现所有组成的纯组分和混合物（IMP + BZCl）在氯化钠中的 值比在水溶液中低，而在U或TU存在下则更高。与U相比，TU在提高纯体系和混合体系的 值方面更有效。所研究的纯体系和混合体系的吉布斯自由能 值为负，表明反应具有自发性。
