Yang Weili, Tang Zhen, Wang Xijin, Ma Xiancang, Cheng Yuqi, Wang Bin, Sun Ping, Tang Wenxin, Luo Jia, Wang Changhong, Li Ping, Xu Guiyun, Yan Jun, Brakoulias Vlasios, Wang Zhen
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, China.
Gen Psychiatr. 2021 Dec 6;34(6):e100632. doi: 10.1136/gpsych-2021-100632. eCollection 2021.
Obsessive-compulsive disorder (OCD) is considered a very debilitating disorder with severe loss of quality of life and income.
This study estimates the quality of life and economic consequences of OCD in China.
The research team interviewed 639 patients with OCD in 13 hospitals in 12 cities in China. The direct method was used to get the direct cost of OCD. Indirect costs associated with OCD were estimated using the human capital approach. Linear regression analysis was conducted for quality of life and generalised linear model analysis was conducted for total cost. Sensitivity analysis was used to analyse the uncertainty of total cost.
The mean quality of life score for OCD was 52.78 (20.46). The annual total cost of OCD per capita was 24 503.78 (95% CI: 22 621.53 to 26 386.03) renminbi (RMB) (US$3465.88 (95% CI: US$3199.65 to US$3732.11)). The annual cost of OCD in China was estimated to be 37.74 billion (95% CI: 34.95 billion to 40.53 billion) RMB (equal to US$5.34 billion (95% CI: US$4.94 billion to US$5.73 billion)). Sensitivity analysis showed that the total annual cost of OCD in China was between 23.15 billion RMB (US$3.27 billion) and 370.00 billion RMB (US$52.33 billion). Worse social function status, more psychiatric symptoms and higher Yale Brown Obsessive-Compulsive Scale (Y-BOCS) score were associated with worse quality of life. The numbers of clinic visits and hospitalisations, socioeconomic status, education, Y-BOCS scores and age were found to be significantly associated with total cost.
OCD is associated with low quality of life and high costs in China. The findings call for concerted efforts to improve services for patients with OCD.Improvements may include early detection and diagnosis, the provision of evidence-based treatments and relapse prevention strategies.
强迫症(OCD)被认为是一种使人极度衰弱的疾病,会导致生活质量和收入严重受损。
本研究评估中国强迫症患者的生活质量及经济后果。
研究团队对中国12个城市13家医院的639名强迫症患者进行了访谈。采用直接法获取强迫症的直接成本。使用人力资本法估算与强迫症相关的间接成本。对生活质量进行线性回归分析,对总成本进行广义线性模型分析。采用敏感性分析来分析总成本的不确定性。
强迫症患者的生活质量平均得分为52.78(20.46)。强迫症人均年度总成本为24503.78元人民币(95%置信区间:22621.53至26386.03元人民币)(3465.88美元(95%置信区间:3199.65至3732.11美元))。据估计,中国强迫症的年度成本为377.4亿元人民币(95%置信区间:349.5亿至405.3亿元人民币)(相当于53.4亿美元(95%置信区间:49.4亿至57.3亿美元))。敏感性分析表明,中国强迫症的年度总成本在231.5亿元人民币(32.7亿美元)至3700.0亿元人民币(523.3亿美元)之间。较差的社会功能状态、更多的精神症状以及更高的耶鲁布朗强迫症量表(Y-BOCS)得分与较差的生活质量相关。门诊就诊次数和住院次数、社会经济状况、教育程度、Y-BOCS得分和年龄被发现与总成本显著相关。
在中国,强迫症与低生活质量和高成本相关。这些发现呼吁各方共同努力改善强迫症患者的服务。改进措施可能包括早期发现和诊断、提供循证治疗以及预防复发策略。