神经刺激治疗功能性神经障碍：一项系统综述。
Neurostimulation for the treatment of functional neurological disorder: A systematic review.
作者信息
Gonsalvez Irene, Spagnolo Primavera, Dworetzky Barbara, Baslet Gaston
机构信息
Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Mary Horrigan Connors Center for Women's Health & Gender Biology, Department of Psychiatry, Brigham and Women Hospital, Harvard Medical School, Boston, MA 02115, USA.
出版信息
Epilepsy Behav Rep. 2021 Nov 9;16:100501. doi: 10.1016/j.ebr.2021.100501. eCollection 2021.
Functional Neurological Disorder (FND), also known as conversion disorder, is characterized by neurological symptoms that are incompatible with any known structural disorder and best explained by a biopsychosocial model. Evidence-based treatments for FND are limited, with cognitive behavioral therapy (CBT) and physiotherapy being the most effective interventions [1]. In recent years, functional neuroimaging studies have provided robust evidence of alterations in activity and connectivity in multiple brain networks in FND. This body of evidence suggests that neurocircuitry-based interventions, such as non-invasive brain stimulation techniques (NIBS), may also represent an effective therapeutic option for patients with FND. In this systematic review, we outline the current state of knowledge of NIBS in FND, and discuss limitations and future directions that may help establish the efficacy of NIBS as a therapeutic option for FND.
功能性神经障碍（FND），也称为转换障碍，其特征是出现与任何已知结构障碍不相符的神经症状，最好用生物心理社会模型来解释。FND的循证治疗方法有限，认知行为疗法（CBT）和物理治疗是最有效的干预措施[1]。近年来，功能性神经影像学研究提供了有力证据，表明FND患者多个脑网络的活动和连接存在改变。这一系列证据表明，基于神经回路的干预措施，如非侵入性脑刺激技术（NIBS），也可能是FND患者的一种有效治疗选择。在本系统评价中，我们概述了NIBS在FND方面的当前知识状态，并讨论了可能有助于确立NIBS作为FND治疗选择有效性的局限性和未来方向。
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