Metcalfe C D, Bayen S, Desrosiers M, Muñoz G, Sauvé S, Yargeau V
Trent University, Peterborough, ON, Canada.
McGill University, Montréal, QC, Canada.
Environ Res. 2022 Apr 15;206:112616. doi: 10.1016/j.envres.2021.112616. Epub 2021 Dec 23.
Endocrine disrupting chemicals (EDCs) are heterogenous in structure, chemical and physical properties, and their capacity to partition into various environmental matrixes. In many cases, these chemicals can disrupt the endocrine systems of vertebrate and invertebrate organisms when present at very low concentrations. Therefore, sensitive and varied analytical methods are required to detect these compounds in the environment. This review summarizes the analytical methods and instruments that are most used to monitor for EDCs in selected environmental matrixes. Only those matrixes for which there is a clear link between exposures and endocrine effects are included in this review. Also discussed are emerging methods for sample preparation and advanced analytical instruments that provide greater selectivity and sensitivity.
内分泌干扰化学物质（EDCs）在结构、化学和物理性质以及它们在各种环境基质中的分配能力方面具有异质性。在许多情况下，这些化学物质在极低浓度下存在时就会干扰脊椎动物和无脊椎动物的内分泌系统。因此，需要灵敏且多样的分析方法来检测环境中的这些化合物。本综述总结了在选定环境基质中监测EDCs最常用的分析方法和仪器。本综述仅纳入了那些暴露与内分泌效应之间存在明确联系的基质。还讨论了新兴的样品制备方法以及提供更高选择性和灵敏度的先进分析仪器。
