再生周围神经接口手术：解剖学与技术指南。

Leach Garrison A, Dean Riley A, Kumar Nishant Ganesh, Tsai Catherine, Chiarappa Frank E, Cederna Paul S, Kung Theodore A, Reid Chris M

From the Department of General Surgery, Division of Plastic Surgery, University of California San Diego, La Jolla, Calif.

Section of Plastic and Reconstructive Surgery and the Department of Biomedical Engineering, University of Michigan, Ann Arbor, Mich.

Plast Reconstr Surg Glob Open. 2023 Jul 17;11(7):e5127. doi: 10.1097/GOX.0000000000005127. eCollection 2023 Jul.

Regenerative peripheral nerve interface (RPNI) surgery has been demonstrated to be an effective tool as an interface for neuroprosthetics. Additionally, it has been shown to be a reproducible and reliable strategy for the active treatment and for prevention of neuromas. The purpose of this article is to provide a comprehensive review of RPNI surgery to demonstrate its simplicity and empower reconstructive surgeons to add this to their armamentarium. This article discusses the basic science of neuroma formation and prevention, as well as the theory of RPNI. An anatomic review and discussion of surgical technique for each level of amputation and considerations for other etiologies of traumatic neuromas are included. Lastly, the authors discuss the future of RPNI surgery and compare this with other active techniques for the treatment of neuromas.

再生周围神经接口（RPNI）手术已被证明是一种有效的工具，可作为神经假体的接口。此外，它已被证明是一种可重复且可靠的策略，用于积极治疗和预防神经瘤。本文的目的是对RPNI手术进行全面综述，以展示其简便性，并使重建外科医生能够将其纳入他们的手术器械库。本文讨论了神经瘤形成和预防的基础科学，以及RPNI的理论。包括对每个截肢水平的手术技术进行解剖学综述和讨论，以及对创伤性神经瘤其他病因的考虑。最后，作者讨论了RPNI手术的未来，并将其与其他治疗神经瘤的积极技术进行比较。