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前列腺癌的外部放射治疗。

External radiotherapy for prostatic cancers.

机构信息

Département de radiothérapie, Centre régional de lutte contre le cancer Eugène-Marquis, 35042 Rennes, France.

Département de radiothérapie, Institut de cancérologie de l'Ouest, Centre René-Gauducheau, 44800 Saint-Herblain, France; Université de Nantes, 44000 Nantes, France.

出版信息

Cancer Radiother. 2022 Feb-Apr;26(1-2):329-343. doi: 10.1016/j.canrad.2021.11.017. Epub 2021 Dec 23.

Abstract

We present the update of the recommendations of the French society of oncological radiotherapy on external radiotherapy of prostate cancer. External radiotherapy is intended for all localized prostate cancers, and more recently for oligometastatic prostate cancers. The irradiation techniques are detailed. Intensity-modulated radiotherapy combined with prostate image-guided radiotherapy is the recommended technique. A total dose of 74 to 80Gy is recommended in case of standard fractionation (2Gy per fraction). Moderate hypofractionation (total dose of 60Gy at a rate of 3Gy per fraction over 4 weeks) in the prostate has become a standard of therapy. Simultaneous integrated boost techniques can be used to treat lymph node areas. Extreme hypofractionation (35 to 40Gy in five fractions) using stereotactic body radiotherapy can be considered a therapeutic option to treat exclusively the prostate. The postoperative irradiation technique, indicated mainly in case of biological recurrence and lymph node involvement, is detailed.

摘要

我们呈现了法国肿瘤放射治疗学会关于前列腺癌外部放射治疗建议的更新。外部放射治疗适用于所有局限性前列腺癌,最近也适用于寡转移前列腺癌。详细介绍了放射治疗技术。调强放疗联合前列腺图像引导放疗是推荐的技术。在标准分割(每次分割 2Gy)的情况下,建议总剂量为 74 至 80Gy。在前列腺中进行适度的超分割(每次分割 3Gy,共 4 周,总剂量 60Gy)已成为治疗标准。同时采用整合增强技术可以治疗淋巴结区域。使用立体定向体部放射治疗进行极超分割(5 次分割,每次 35 至 40Gy)可被视为一种专门治疗前列腺的治疗选择。详细介绍了术后照射技术,主要适用于生物学复发和淋巴结受累的情况。

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