Sección de Dermatología, Hospital Dr. José Molina Orosa, Lanzarote, Provincia de Las Palmas, Spain.
Servicio de Neurocirugía, Hospital Universitario de Gran Canaria Doctor Negrín, Provincia de Las Palmas, Spain.
Neurocirugia (Astur : Engl Ed). 2022 Jan-Feb;33(1):46-50. doi: 10.1016/j.neucie.2020.11.003. Epub 2021 Dec 23.
Neutrophilic dermatoses include a heterogeneous group of entities. Uncommonly, they can accumulate aseptic neutrophilic abscesses in other tissues in addition to the skin. A 34-year-old female complained of a headache which was unresponsive to usual drugs. A TAC revealed an osteolytic lesion in the right parietal bone. The biopsy showed osteomyelitis. One year later, pyoderma gangrenosum appeared in the anterior aspect of both legs. The headache and the cutaneous lesions disappeared after treatment with oral prednisone. The bone involvement in the background of neutrophilic dermatoses is exceptional. Usually, it involves children in the context of chronic recurrent multiple osteomyelitis (CRMO). Only two cases have been described in adults. One of them was a 26-year-old woman who had had CRMO since childhood, and the other one in contiguity with the cutaneous lesions of pyoderma gangrenosum.
中性粒细胞皮肤病包括一组异质性实体。罕见情况下，除皮肤外，它们还会在其他组织中积累无菌性中性粒细胞脓肿。一位 34 岁女性主诉头痛，通常的药物对此无效。TAC 显示右顶骨溶骨性病变。活检显示骨髓炎。一年后，双小腿前出现坏疽性脓皮病。口服泼尼松治疗后，头痛和皮肤病变消失。中性粒细胞皮肤病背景下的骨骼受累是罕见的。通常，它发生在儿童慢性复发性多灶性骨髓炎（CRMO）中。仅在成人中描述了两例。其中一例是一名 26 岁女性，自童年起即患有 CRMO，另一例与坏疽性脓皮病的皮肤病变相邻。
