Cochran G V, Johnson M W, Kadaba M P, Palmieri V R, Mahaffey G
J Rehabil Res Dev. 1987 Spring;24(2):39-50.
The piezoelectric internal fixation plate represents a new concept in orthopaedic implants. The purpose of this device is to provide stable bone fixation while delivering internally generated, microampere direct currents to prevent or treat nonunion of a fracture or osteotomy. Clinically, currents of this type have been effective in treatment of nonunion, but application has required separate, implanted, or external battery or radiofrequency powered circuits. The "piezoplate" being developed contains an integral piezoelectric element that generates current in response to either physiological loading such as weightbearing or to externally applied ultrasound. Currents are processed by a rectifying circuit for delivery to bone by electrodes. Specially designed series/parallel piezoelectric elements and dual processing circuits are required to generate optimum rectified currents from the low-frequency, high-voltage signals generated by weightbearing, as well as the high-frequency, low-voltage signals produced by ultrasound. This paper reports on the current status of development and describes design parameters of this device which combines the modalities of mechanical fixation and electrical stimulation in a single implant.
压电内固定板代表了骨科植入物的一个新概念。该装置的目的是在提供稳定的骨固定的同时，输送内部产生的微安直流电，以预防或治疗骨折或截骨术的骨不连。临床上，这类电流在治疗骨不连方面已取得成效，但应用时需要单独的植入式或外置电池或射频供电电路。正在研发的“压电板”包含一个集成压电元件，该元件可响应诸如负重等生理负荷或外部施加的超声波而产生电流。电流由整流电路处理后通过电极输送至骨骼。需要专门设计的串联/并联压电元件和双处理电路，以便从负重产生的低频、高压信号以及超声波产生的高频、低压信号中生成最佳整流电流。本文报告了该装置的当前研发状况，并描述了这种在单个植入物中结合了机械固定和电刺激方式的装置的设计参数。
