Cochran G V, Johnson M W, Kadaba M P, Vosburgh F, Ferguson-Pell M W, Palmieri V R
J Orthop Res. 1985;3(4):508-13. doi: 10.1002/jor.1100030414.
Prototype testing has been accomplished on a piezoelectric, internal fixation plate. This device combines a piezoelectric material with an internal fixation device as an integrated structure that provides mechanical stability, together with self-generated electrical stimulation, for treating fractures and nonunion. In bench and animal tests we have demonstrated that cyclical loading can cause a device of this type to generate electrical charge while attached to bone. After rectification, direct currents within the range known to stimulate osteogenesis can be produced by weight-bearing loads. Furthermore, electrical output of the implants can be increased by externally applied ultrasonic energy. These twin developments add significantly to the potential armamentarium of devices to enhance bone healing.
已经对一种压电内固定板进行了原型测试。该装置将压电材料与内固定装置结合为一个整体结构，可提供机械稳定性以及自生电刺激，用于治疗骨折和骨不连。在实验室和动物试验中，我们已经证明，这种类型的装置在附着于骨骼时，周期性加载可使其产生电荷。经过整流后，负重载荷可产生已知能刺激成骨的直流电范围。此外，通过外部施加超声能量可增加植入物的电输出。这两项进展显著增加了用于促进骨愈合的潜在器械库。
