Kühne G E, Grünes J U, Knorr W, Perina L, Richter H, Rommel U, Sorger R, Stöck H, Waldow N
Psychiatr Neurol Med Psychol (Leipz). 1978 Feb;30(2):104-15.
The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.
在一项对照临床实验条件下进行的多临床研究框架内，对去甲丙咪嗪和丙咪嗪这两种抗抑郁药进行了比较。发现情感症状有时间差异的缓解，而在抑制驱力方面未检测到这种差异。参照这些结果对去甲丙咪嗪的精神运动性兴奋抑制作用进行了讨论。对控制情感可能性的评估显示，去甲丙咪嗪和丙咪嗪的活性范围不同，去甲丙咪嗪尤其影响驱力和情绪领域的负面心理能量症状，而丙咪嗪除了影响精神运动表现的差异现象外，还影响限制性症状。
