Barbot D J, Rosato E F
Surgery. 1987 Jun;101(6):685-90.
Twenty-eight consecutive unselected patients were treated for esophageal varices by means of a modified Sugiura procedure between 1978 and 1985. In accordance with Child's classification, 59% were considered as class A, 11% as class B, and 30% as class C. The etiology of the cirrhosis included alcohol abuse (42%), hepatitis (33%), granulomatous disease (7%), and cryptogenic disease (18%). One patient had extrahepatic portal hypertension from unknown causes. The surgical treatment included esophageal and gastric devascularization in all cases. The average operative time was 4 1/2 hours. The average blood replacement during surgery was 8 units. The operative mortality was 32% (2/16 class A, 1/3 class B, and 6/9 class C). Morbidity occurred in 33% of the patients. Significant causes of morbidity and mortality were related to complications of the esophageal transection, which was omitted in the later series. Six of the eighteen patients who survived surgery died later, but only one death was due to presumed recurrent variceal hemorrhage. Significant bleeding occurred in four patients--two due to recurrent varices and two due to peptic ulcer disease. Encephalopathy, which was present preoperatively in two patients, is still manifest but is well controlled. Encephalopathy did not develop in any other patients. At present, the 12 surviving patients have stable liver function.
1978年至1985年间,对28例未经挑选的连续性患者采用改良的杉浦手术治疗食管静脉曲张。根据Child分级,59%的患者为A级,11%为B级,30%为C级。肝硬化的病因包括酒精滥用(42%)、肝炎(33%)、肉芽肿病(7%)和隐源性疾病(18%)。1例患者患有不明原因的肝外门静脉高压。所有病例的手术治疗均包括食管和胃去血管化。平均手术时间为4.5小时。手术期间平均输血量为8个单位。手术死亡率为32%(A级16例中的2例,B级3例中的1例,C级9例中的6例)。33%的患者发生了并发症。并发症和死亡的主要原因与食管横断的并发症有关,在后来的系列病例中省略了食管横断。18例手术后存活的患者中有6例后来死亡,但只有1例死亡被认为是由于曲张静脉复发出血。4例患者发生了严重出血,2例由于曲张静脉复发,2例由于消化性溃疡病。术前有2例患者存在脑病,目前仍有表现但得到了很好的控制。其他患者均未发生脑病。目前,12例存活患者的肝功能稳定。