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首例犬感染[病原体名称未给出]所致的细菌性心内膜炎 。

The First Bacterial Endocarditis Due to in a Dog.

作者信息

Steiner Verena, Rosel Adriana Cabal, Ruppitsch Werner, Allerberger Franz, Carranza Valencia Alejandra, Markovic Mato, Luckschander-Zeller Nicole, Szostak Michael P, Spergser Joachim, Loncaric Igor, Künzel Frank

机构信息

Department for Companion Animals and Horses, Clinical Unit of Internal Medic and Small Animals, University of Veterinary Medicine, 1210 Vienna, Austria.

Institute of Medical Microbiology and Hygiene, Austrian Agency for Health and Food Safety, 1090 Vienna, Austria.

出版信息

Pathogens. 2021 Dec 3;10(12):1580. doi: 10.3390/pathogens10121580.

Abstract

Infectious endocarditis (IE) in dogs is often associated with a high mortality rate as diagnostic work-up as well as antibiotic treatment might be challenging. The present case describes bacteremia in a dog caused by   leading to an infectious endocarditis. ( ) is an aerobic Gram-negative rod-shaped bacterium, which has been associated with multiple nosocomial opportunistic diseases in human medicine. One such manifestation of   infection is endocarditis.   infections are challenging to treat due to the reduced effectiveness of a wide range of antimicrobial agents. To date, only a few case reports of infections with   in animals have been described. This is the first case report of   endocarditis in a dog. Whole-genome sequencing was performed to determine the sequencing type and to gain more information about this bacterium regarding its intrinsic resistance genes. With this case report, we seek to increase awareness of as an opportunistic nosocomial pathogen in dogs and to provide a short summary regarding the current state of general knowledge and known resistance patterns.

摘要

犬感染性心内膜炎(IE)的死亡率通常较高,因为诊断检查和抗生素治疗可能具有挑战性。本病例描述了一只犬因 导致感染性心内膜炎的菌血症。( )是一种需氧革兰氏阴性杆菌,在人类医学中与多种医院获得性机会性疾病有关。 感染的一种表现形式是心内膜炎。由于多种抗菌药物的有效性降低, 感染的治疗具有挑战性。迄今为止,仅描述了少数动物感染 的病例报告。这是首例犬 心内膜炎的病例报告。进行全基因组测序以确定测序类型,并获取有关该细菌固有耐药基因的更多信息。通过本病例报告,我们旨在提高对 作为犬机会性医院病原体的认识,并提供有关一般知识现状和已知耐药模式的简短总结。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fdb/8709460/9e8d698f17e4/pathogens-10-01580-g001.jpg

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