Wehrmann W, Bauer R, Fuchs D, Hausen A, Reibnegger G, Werner E R, Wachter H
Eur J Clin Microbiol. 1987 Apr;6(2):210-1. doi: 10.1007/BF02018218.
A patient with mycosis fungoides was treated effectively with the immunosuppressant cyclosporine A. Excretion of urinary neopterin, a marker of activation of the cellular immune system, fell immediately at the start of therapy. This result argues in support of a central role of activated T lymphocytes in this disease as has already been proposed by other authors.
一名蕈样肉芽肿患者接受免疫抑制剂环孢素A治疗后效果显著。尿新蝶呤是细胞免疫系统激活的标志物,在治疗开始时其排泄量立即下降。这一结果支持了其他作者已经提出的活化T淋巴细胞在该疾病中起核心作用的观点。