肌醇1,4,5-三磷酸和5'-鸟苷三磷酸从不同的细胞内池诱导钙释放。
Inositol 1,4,5-trisphosphate and 5'-GTP induce calcium release from different intracellular pools.
作者信息
Henne V, Piiper A, Söling H D
出版信息
FEBS Lett. 1987 Jun 22;218(1):153-8. doi: 10.1016/0014-5793(87)81037-2.
PMID:3496244
Abstract
It has been shown recently by several groups that 5'-GTP can release calcium from intracellular compartments independently from inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) by a mechanism which seems to be different from that used by Ins(1,4,5)P3. We report here for the first time that the 5'-GTP-sensitive and the Ins(1,4,5)P3-sensitive calcium pools reside in different intracellular compartments.
摘要
最近有几个研究小组表明，5'-鸟苷三磷酸（5'-GTP）可通过一种似乎不同于1,4,5-三磷酸肌醇（Ins(1,4,5)P3）所采用的机制，独立于Ins(1,4,5)P3从细胞内区室释放钙。我们在此首次报道，对5'-GTP敏感的钙池和对Ins(1,4,5)P3敏感的钙池存在于不同的细胞内区室中。
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