Luoyang Central Hospital, Zhengzhou University, China.
Henan Provincial People's Hospital, Zhengzhou University, China.
Medicine (Baltimore). 2021 Nov 24;100(47):e27798. doi: 10.1097/MD.0000000000027798.
Postpartum cerebral arterial dissections are rare, and the clinical features, diagnosis, and treatment approaches are not clear to many physicians. This study was to investigate the clinical features, diagnosis, and treatment of postpartum cerebral arterial dissections.One patient with postpartum cerebral arterial dissections enrolled in our hospital was analyzed. All patients with postpartum cerebral arterial dissections retrieved from the PubMed were also included in this study and analyzed.A total of 45 patients with postpartum cerebral arterial dissections were retrieved including our case, with an age range of 24 to 44 years (mean 34). Thirty-six (80%) patients were older than 30 years of age (mean 35). There were 17 cases of cesarean section, 14 cases of natural labor, and 14 cases whose delivery modes were not reported. The clinical symptoms included headache in 35 cases (78%) and neck pain in 14 (31%). The symptoms occurred at a mean time of 11 days (range 0-53 days) following delivery. Among 45 patients, arterial dissections involved unilateral carotid or vertebral artery in 29 cases (64%), bilateral carotid or vertebral arteries in 8 (18%), 3 arteries in 3 (7%), and all bilateral carotid and vertebral arteries in 5 (11%). Fourteen (31%) patients were treated with antiplatelet agents, 27 (60%) with anticoagulation, 7 (16%) with both antiplatelet and anticoagulation medications, and only 2 (4%) with stent angioplasty. The prognosis was complete recovery in 30 (86%) patients and mild focal neurological symptoms in 5 (14%).Postpartum cerebral arterial dissections are rare, and correct diagnosis relies on imaging examination. Prognosis is usually favorable in patients with early diagnosis and prompt treatment.
产后脑动脉夹层较为罕见,许多医生并不清楚其临床特征、诊断和治疗方法。本研究旨在探讨产后脑动脉夹层的临床特征、诊断和治疗方法。
分析了我院收治的 1 例产后脑动脉夹层患者。还对从 PubMed 检索到的所有产后脑动脉夹层患者进行了分析。
共检索到 45 例产后脑动脉夹层患者,包括我院的病例,年龄范围为 24 至 44 岁(平均 34 岁)。36 例(80%)患者年龄大于 30 岁(平均 35 岁)。其中 17 例为剖宫产,14 例为自然分娩,14 例分娩方式未报道。临床症状包括头痛 35 例(78%)和颈部疼痛 14 例(31%)。症状发生在产后 11 天(0-53 天)。45 例患者中,单侧颈内或椎动脉夹层 29 例(64%),双侧颈内或椎动脉夹层 8 例(18%),3 动脉夹层 3 例(7%),双侧颈内和椎动脉夹层 5 例(11%)。14 例(31%)患者接受抗血小板治疗,27 例(60%)接受抗凝治疗,7 例(16%)接受抗血小板和抗凝药物治疗,仅 2 例(4%)接受支架血管成形术。30 例(86%)患者预后完全恢复,5 例(14%)患者遗留轻度局灶性神经症状。
产后脑动脉夹层较为罕见,正确诊断依赖于影像学检查。早期诊断和及时治疗的患者预后通常良好。