Department of Dermatology, Baylor Scott & White, Temple, TX.
Twin Ports Dermatology, Duluth, MN.
Am J Dermatopathol. 2022 Apr 1;44(4):276-278. doi: 10.1097/DAD.0000000000002120.
Panfolliculomas (PF) are rare, benign, follicular tumors that differentiate toward multiple components of the hair follicle, and several variants have been described. We present a case of a rare pigmented PF presenting on actinically damaged skin in an 83-year-old man, which was clinically concerning for malignancy. This tumor arose near an area of atypical squamous proliferation and has evidence of infundibular, outer root sheath, and matrical differentiation and foci of heavy melanin pigmentation and increased melanocytes. We propose the novel designation of "melanocytic PF," akin to melanocytic matricoma but with panfollicular differentiation.
毛囊瘤（PF）是一种罕见的良性毛囊肿瘤，可向毛发生长的多个成分分化，并且已经描述了几种变体。我们报告了一例罕见的色素性 PF 病例，发生在 83 岁男性的光损伤皮肤上，临床上令人担忧为恶性肿瘤。该肿瘤发生在非典型鳞状增生区域附近，具有内囊、外根鞘和基质分化的证据，并有大量黑色素沉着和黑色素细胞增多的病灶。我们提出了“黑色素细胞性 PF”的新命名，类似于黑色素细胞瘤，但具有全毛囊分化。
