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一例酷似基底细胞癌的耳后全毛囊瘤:一种罕见的附属器肿瘤并文献复习

A case of retro-auricular panfolliculoma mimicking basal cell carcinoma: A rare adnexal tumor with a review of the literature.

作者信息

Al-Zahawi Saman, Ghanadan Alireza, Etesami Ifa

机构信息

Department of dermatology, Razi hospital Tehran University of Medical Sciences (TUMS) Tehran Iran.

Department of dermatopathology, Razi hospital Tehran University of Medical Sciences (TUMS) Tehran Iran.

出版信息

Clin Case Rep. 2023 Sep 7;11(9):e7874. doi: 10.1002/ccr3.7874. eCollection 2023 Sep.

DOI:10.1002/ccr3.7874
PMID:37692159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10485239/
Abstract

KEY CLINICAL MESSAGE

A rare case of slow-growing retro-auricular panfolliculoma is presented. The lesion was biopsied to rule out basal cell carcinoma but histopathology revealed a follicular tumor with differentiation toward all segments of the hair follicle. Panfolliculoma is a benign follicular tumor with no report of recurrence after surgical excision and no malignant transformation of the previously reported cases.

ABSTRACT

Panfolliculoma is a rare slow growing adnexal tumor, characterized by differentiation toward all parts of the hair follicle including the infundibulum, isthmus, stem, and bulbs. Clinically this adnexal tumor may mimick basal cell carcinoma and other adnexal neoplasm including trichoblastoma and trichoepithelioma. In this study, we present a rare case of slow-growing retro-auricular panfolliculoma of a 70-year-old female mimicking basal cell carcinoma that was successfully excised without recurrence.

摘要

关键临床信息

报告了一例罕见的生长缓慢的耳后全毛囊瘤病例。对该病变进行活检以排除基底细胞癌,但组织病理学显示为一种向毛囊各节段分化的毛囊肿瘤。全毛囊瘤是一种良性毛囊肿瘤,手术切除后无复发报告,且既往报道的病例均无恶变。

摘要

全毛囊瘤是一种罕见的生长缓慢的附属器肿瘤,其特征是向毛囊的所有部分分化,包括漏斗部、峡部、茎部和球部。临床上,这种附属器肿瘤可能会模仿基底细胞癌和其他附属器肿瘤,包括毛母细胞瘤和毛发上皮瘤。在本研究中,我们报告了一例罕见的70岁女性耳后生长缓慢的全毛囊瘤病例,该病例模仿基底细胞癌,已成功切除且无复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/d1fb099edd29/CCR3-11-e7874-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/f98134a5e22f/CCR3-11-e7874-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/e222ec283be8/CCR3-11-e7874-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/5b3170e2d8ab/CCR3-11-e7874-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/d1fb099edd29/CCR3-11-e7874-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/f98134a5e22f/CCR3-11-e7874-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/e222ec283be8/CCR3-11-e7874-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/5b3170e2d8ab/CCR3-11-e7874-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f355/10485239/d1fb099edd29/CCR3-11-e7874-g005.jpg

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本文引用的文献

1
Panfolliculoma: Report of the Youngest Case and Literature Review of Its Histopathologic Variants.全毛囊瘤:最年轻病例报告及其组织病理学变异的文献综述
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2
Melanocytic Panfolliculoma: A Case Report of a Rare Benign Follicular Tumor.黑素细胞全滤泡瘤:一种罕见良性滤泡肿瘤的病例报告。
Am J Dermatopathol. 2022 Apr 1;44(4):276-278. doi: 10.1097/DAD.0000000000002120.
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Panfolliculoma: A Clinical Case Report.全毛囊瘤:一例临床病例报告。
Int J Trichology. 2017 Oct-Dec;9(4):187-189. doi: 10.4103/ijt.ijt_43_17.
4
Immunohistochemical dissection of cystic panfolliculoma focusing on the expression of multiple hair follicle lineage markers with an insight into the pathogenesis.囊性全毛囊瘤的免疫组织化学剖析:聚焦多种毛囊谱系标志物的表达并深入探讨其发病机制
J Cutan Pathol. 2017 Oct;44(10):861-866. doi: 10.1111/cup.12992. Epub 2017 Jul 24.
5
A rare cutaneous adnexal neoplasm: cystic panfolliculoma.一种罕见的皮肤附属器肿瘤:囊性全毛囊瘤。
J Cutan Pathol. 2016 Dec;43(12):1183-1185. doi: 10.1111/cup.12807. Epub 2016 Sep 26.
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Panfolliculoma and histopathologic variants: a study of 19 cases.全毛囊瘤及其组织病理学变异型:19例研究
Am J Dermatopathol. 2014 Dec;36(12):965-71. doi: 10.1097/DAD.0000000000000108.
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Cystic panfolliculoma of the scalp: report of a very rare case and brief review.头皮囊性全毛囊瘤:1例极罕见病例报告及简要文献复习
Indian J Pathol Microbiol. 2013 Oct-Dec;56(4):437-9. doi: 10.4103/0377-4929.125363.
8
Panfolliculoma with sebaceous differentiation--a case report.伴有皮脂腺分化的全毛囊瘤——病例报告
Am J Dermatopathol. 2012 Oct;34(7):e90-3. doi: 10.1097/DAD.0b013e31824c22fb.
9
Epidermal panfolliculoma: A report of 2 cases.表皮全毛囊瘤:2例报告。
Am J Dermatopathol. 2011 Feb;33(1):e7-10. doi: 10.1097/dad.0b013e3181d94d3e.
10
[Immunohistochemical study of calretinin in normal hair follicles and tumors with follicular differentiation].[正常毛囊及具有毛囊分化的肿瘤中钙结合蛋白的免疫组织化学研究]
Actas Dermosifiliogr. 2008 Jul-Aug;99(6):456-63.