Bangolo Ayrton, Bukasa Kakamba John, Atoot Ali, Jurri Mohammad, Mahmoud Ashraf, Lo Arthur Oliver, Song Kunchang, Sirajuddin Syed, Atoot Adam
Department of Internal Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, NJ, USA.
Endocrine and Metabolic Disorders Department, University Clinics of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Case Rep Endocrinol. 2021 Dec 21;2021:5231703. doi: 10.1155/2021/5231703. eCollection 2021.
Sarcoidosis is a multisystem inflammatory disease characterized by the presence of noncaseating granulomas. Sarcoidosis can affect any organ of the body, the lung being the most affected. Sarcoidosis rarely affects the thyroid gland, and only a few cases of thyroid-related sarcoidosis have been reported in the literature. Herein, we report a case of systemic sarcoidosis with multiple organ involvement in a patient with a solitary left thyroid nodule and benign Fine Needle Aspiration (FNA) findings. The patient was eventually diagnosed with thyroid sarcoidosis using a core needle biopsy of the thyroid nodule. With this case report, we highlight the limitations of the FNA. This case report has the objective to encourage clinicians to include thyroid sarcoidosis in the differential diagnosis of thyroid nodules in patients with systemic sarcoidosis even with unremarkable FNA findings.
结节病是一种多系统炎症性疾病,其特征是存在非干酪样肉芽肿。结节病可累及身体的任何器官,其中肺部受累最为常见。结节病很少累及甲状腺,文献中仅报道了少数几例与甲状腺相关的结节病病例。在此,我们报告一例系统性结节病患者,该患者有多个器官受累,同时伴有左侧甲状腺孤立性结节,细针穿刺活检(FNA)结果为良性。最终通过对甲状腺结节进行粗针活检,该患者被诊断为甲状腺结节病。通过本病例报告,我们强调了FNA的局限性。本病例报告旨在鼓励临床医生,即使FNA结果无异常,在系统性结节病患者甲状腺结节的鉴别诊断中也应考虑甲状腺结节病。