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COVID-19 阴性患者的血管实践减少和心血管死亡率增加。

Reduced Vascular Practice and Increased Cardiovascular Mortality for COVID-19-Negative Patients.

机构信息

Vascular and Endovascular Surgery Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Anesthesiology and Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

出版信息

J Surg Res. 2022 Apr;272:146-152. doi: 10.1016/j.jss.2021.11.014. Epub 2021 Dec 9.

DOI:10.1016/j.jss.2021.11.014
PMID:34973548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8654577/
Abstract

BACKGROUND

The aim of our study was to compare COVID-19- and not-COVID-19-related mortality rates in two Italian regions during the pandemic period when the same isolation rules and therapeutic approaches were introduced for all hospitals in Italy. Risk factors for not-COVID-19-related deaths during the pandemic were analyzed; we tried to assess a possible correlation between reducing hospital visits and "deferrable" vascular operations and the increased cardiovascular mortality not related to COVID-19 infection.

METHODS

We analyzed COVID-19- and not-COVID-19-related mortality rates in two Italian regions in the period January 2020-January 2021. We compared mortality rates during the pandemic period with those of the previous five years. We tried to determine the factors involved in increased mortality rates during the pandemic period.

RESULTS

Despite the same isolation rules for people and the same therapeutic approaches for hospitals, mortality rates did not increase in the region Lazio, where the pandemic was not severe. In the region Lombardy, the mortality rate was doubled in comparison with the previous years, and 50% of the increase was related to not-COVID-19 deaths.

CONCLUSIONS

The increase in mortality rates for not-COVID-19-related deaths in the region Lombardy was connected to the generalized turmoil in the acute phase of an overwhelming pandemic, including diffuse stress, inadequate communications, reluctance to ask for medical help unless symptoms were severe, and unexpected inadequate number of health workers, hospital beds, and intensive care unit beds. Reduced hospital visits may have had a fundamental role.

摘要

背景

本研究旨在比较意大利两个地区在大流行期间的 COVID-19 相关死亡率和非 COVID-19 相关死亡率,当时意大利所有医院都采用了相同的隔离规定和治疗方法。分析了大流行期间非 COVID-19 相关死亡的危险因素;我们试图评估减少医院就诊次数和“可延迟”血管手术与非 COVID-19 感染相关的心血管死亡率增加之间是否存在相关性。

方法

我们分析了 2020 年 1 月至 2021 年 1 月意大利两个地区的 COVID-19 相关死亡率和非 COVID-19 相关死亡率。我们将大流行期间的死亡率与前五年的死亡率进行了比较。我们试图确定大流行期间死亡率增加的相关因素。

结果

尽管对人和医院采用了相同的隔离规定和相同的治疗方法,但在疫情不严重的拉齐奥地区,死亡率并没有增加。在伦巴第地区,死亡率与前几年相比翻了一番,其中 50%的增加与非 COVID-19 死亡有关。

结论

伦巴第地区非 COVID-19 相关死亡人数增加与压倒性大流行急性期的普遍混乱有关,包括弥漫性压力、沟通不足、除非症状严重否则不愿寻求医疗帮助,以及出乎意料的卫生工作者、医院床位和重症监护室床位不足。减少医院就诊可能起了重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aff/8654577/672afe8ee443/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aff/8654577/768f062bc04a/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aff/8654577/672afe8ee443/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aff/8654577/768f062bc04a/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aff/8654577/672afe8ee443/gr2_lrg.jpg

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