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心脏手术中浓缩引流血的术后自体输血。一种新型自体输血系统的经验。

Postoperative autotransfusion of concentrated drainage blood in cardiac surgery. Experience with a new autotransfusion system.

作者信息

Solem J O, Olin C, Tengborn L, Nordin G, Lührs C, Steen S

出版信息

Scand J Thorac Cardiovasc Surg. 1987;21(2):153-7. doi: 10.3109/14017438709106514.

DOI:10.3109/14017438709106514
PMID:3497445
Abstract

A new autotransfusion system was evaluated postoperatively in six patients undergoing aortocoronary bypass surgery. A hollow fiber hemofilter was integrated in the system, making it possible to concentrate the shed blood. The device functioned well, 825 ml diluted mediastinal drainage blood with a hematocrit of 23 was concentrated to a volume of 475 ml with a hematocrit of 36 and retransfused. Proteins were preserved, thus albumin concentration increased from 23 to 37 g/l in the autotransfusate. No negative side effects were registered after autotransfusion. A thorough coagulation study after retransfusion did not reveal any sign of activation of the coagulation cascade, nor were there any signs of an increased fibrinolysis.

摘要

一种新型自体输血系统在6例接受主动脉冠状动脉搭桥手术的患者术后进行了评估。该系统集成了中空纤维血液滤过器,使浓缩引流血成为可能。该装置运行良好,825毫升血细胞比容为23%的稀释纵隔引流血被浓缩至475毫升,血细胞比容为36%后回输。蛋白质得以保留,因此自体回输血中白蛋白浓度从23克/升增加到37克/升。自体输血后未出现负面副作用。回输后进行的全面凝血研究未发现凝血级联激活的任何迹象,也没有纤维蛋白溶解增加的迹象。

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Postoperative autotransfusion of concentrated drainage blood in cardiac surgery. Experience with a new autotransfusion system.心脏手术中浓缩引流血的术后自体输血。一种新型自体输血系统的经验。
Scand J Thorac Cardiovasc Surg. 1987;21(2):153-7. doi: 10.3109/14017438709106514.
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Autotransfusion in coronary artery bypass grafting: disparity in laboratory tests and clinical performance.冠状动脉搭桥术中的自体输血:实验室检查与临床表现的差异
J Thorac Cardiovasc Surg. 1999 Oct;118(4):610-7. doi: 10.1016/s0022-5223(99)70005-x.
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Mediastinal drainage blood. Potentialities for autotransfusion after cardiac surgery.纵隔引流血。心脏手术后自体输血的可能性。
Scand J Thorac Cardiovasc Surg. 1987;21(2):149-52. doi: 10.3109/14017438709106513.
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Autotransfusion after open heart surgery: the oxygen delivery capacity of shed mediastinal blood is maintained.心脏直视手术后的自体输血:纵隔引流血的氧输送能力得以维持。
Acta Anaesthesiol Scand. 1995 Aug;39(6):754-8. doi: 10.1111/j.1399-6576.1995.tb04165.x.
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Autotransfusion of washed shed mediastinal fluid decreases the requirement for autologous blood transfusion following cardiac surgery: a prospective randomized trial.心脏手术后,回输洗涤后的纵隔引流液可减少自体输血需求:一项前瞻性随机试验
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[Blood conservation effect and safety of shed mediastinal blood autotransfusion after cardiac surgery].[心脏手术后纵隔引流血自体输血的血液保护效果及安全性]
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Reinfusion of mediastinal blood after heart surgery.
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Autotransfusion management during and after cardiopulmonary bypass alters fibrin degradation and transfusion requirements.体外循环期间及之后的自体输血管理会改变纤维蛋白降解和输血需求。
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