Hersant Jeanne, Ramondou Pierre, Douillet Delphine, Abrard Stanislas, Vandeputte Patrick, Lapébie François-Xavier, Abraham Pierre, Henni Samir
Vascular Medicine, University Hospital Center, Angers, France.
Emergency, University Hospital Center, Angers, France.
Ultrasonography. 2022 Apr;41(2):373-381. doi: 10.14366/usg.21175. Epub 2021 Nov 10.
This study investigated the correlations of hemodynamic parameters measured to quantify stenosis between the gold-standard duplex ultrasonography and the dual-gate Doppler mode.
Patients examined due to suspicion of carotid artery stenosis or for surveillance of known stenosis were invited to participate in this prospective single-center study. Upon acceptance, the hemodynamic characteristics of the carotid arteries were determined successively in standard duplex and dual-gate Doppler modes. The correlations between the two modes were analyzed by computing Pearson coefficients (r2) and Lin concordance coefficients (ρc). The degree of agreement between the two methods was visualized using Bland-Altman graphical representations.
The correlation between internal carotid artery peak systolic velocity measured by standard duplex ultrasonography and dual-gate Doppler mode was good (r2=0.642). The same high level of correlation was observed for the carotid ratio (r2=0.544). However, the Bland-Altman graphical representation and the Lin concordance coefficients (ρc=0.75 and ρc=0.74 for the internal carotid artery peak systolic velocity and carotid ratio, respectively) showed that a lack of precision generated some discrepancies between the two measurement methods.
Although some discrepancies were observed, the hemodynamic measurements were closely correlated between the two ultrasonography modes. Therefore, the dual-gate Doppler mode may have obvious advantages over conventional ultrasonography, offering interesting development possibilities.
本研究调查了用于量化狭窄的血流动力学参数在金标准双功超声与双门控多普勒模式之间的相关性。
因怀疑颈动脉狭窄或对已知狭窄进行监测而接受检查的患者被邀请参加这项前瞻性单中心研究。入选后，依次采用标准双功和双门控多普勒模式测定颈动脉的血流动力学特征。通过计算皮尔逊系数（r2）和林一致性系数（ρc）分析两种模式之间的相关性。使用布兰德-奥特曼图形表示法直观显示两种方法之间的一致性程度。
标准双功超声测定的颈内动脉收缩期峰值流速与双门控多普勒模式之间的相关性良好（r2 = 0.642）。颈动脉比值也观察到同样高的相关性水平（r2 = 0.544）。然而，布兰德-奥特曼图形表示法以及林一致性系数（颈内动脉收缩期峰值流速和颈动脉比值的ρc分别为0.75和0.74）表明，缺乏精确性导致两种测量方法之间存在一些差异。
尽管观察到一些差异，但两种超声模式之间的血流动力学测量密切相关。因此，双门控多普勒模式可能比传统超声具有明显优势，提供了有趣的发展可能性。
