Mohagheghi Parisa, Hakimelahi Javad, Khalajinia Zohreh, Sadeghi Moghadam Parvaneh
Department of Pediatrics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Department of Pediatrics, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
Tanaffos. 2021 Feb;20(2):172-179.
The symptoms, severity, and prognosis of coronavirus disease 2019 (COVID-19) are surprisingly different in neonates versus adults or even children. Currently, there are few studies on neonatal and maternal COVID-19 with limited populations.
In this study, we present 13 Iranian symptomatic newborns with a positive nasopharyngeal COVID-19 test and their maternal data on COVID-19. All neonates were admitted to the hospital at the first day of life, mostly having symptoms at birth, except three cases that had symptoms at days 2, 11, and 22. Almost all cases had respiratory distress and were tachypneic, which needed respiratory support. Although most cases were discharged after recovery, two patients died at days 12 and 48.
Neonatal COVID-19 cases mostly had respiratory symptoms and subsequent radiographic features of a viral pneumonia; thus, they had an effective response to oxygen therapy. The symptoms were by far less severe in newborns, although we lost two cases to this infection. This highlights the necessity for good COVID-19 prognosis in infants and neonates.
2019冠状病毒病（COVID-19）在新生儿中的症状、严重程度和预后与成人甚至儿童相比差异惊人。目前，关于新生儿和母亲COVID-19的研究较少，且样本量有限。
在本研究中，我们报告了13例鼻咽部COVID-19检测呈阳性的有症状伊朗新生儿及其母亲的COVID-19数据。所有新生儿均在出生第一天入院，大多数在出生时即有症状，只有3例分别在出生后第2天、第11天和第22天出现症状。几乎所有病例都有呼吸窘迫和呼吸急促，需要呼吸支持。尽管大多数病例康复后出院，但有2例患者分别在第12天和第48天死亡。
新生儿COVID-19病例大多有呼吸道症状及随后出现的病毒性肺炎影像学特征；因此，他们对氧疗有有效反应。尽管有2例患者死于该感染，但新生儿的症状远没有那么严重。这凸显了改善婴儿和新生儿COVID-19预后的必要性。
