Wang Hui, Cui Jingjing, Zhao Shitong, Xu Dongsheng, Wu Shuang, Bai Wanzhu, Wang Jia
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Center for Experimental Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China.
Evid Based Complement Alternat Med. 2021 Dec 23;2021:1401756. doi: 10.1155/2021/1401756. eCollection 2021.
To collect and summarize relevant literatures on the experimental researches of sciatic nerve injury (SNI) with acupuncture during the last decade providing a guideline for effectively treating SNI with acupuncture in the future.
The Chinese and English databases including China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform (WanFang Data), VIP Information Chinese Journal Service Platform (VIP Date), and PubMed were searched from 2009 to 2020 with keywords of "acupuncture and moxibustion OR acupuncture OR electroacupuncture OR scalp acupuncture OR wrist-ankle acupuncture OR acupoint injection OR ear acupuncture" AND "sciatic nerve OR sciatic nerve injury OR sciatic injury OR SNI." The collected data were mainly evaluated in the items of animal model of SNI, type of interventions, selection of acupuncture points (acupoints), course of treatment and its frequency, and approaches of assessment.
A total of 89 studies were included in this analysis. Among them, the most commonly used animal models of SNI were produced by the clamp or transverse injury in the rats; the most frequently used intervention was electroacupuncture with dilatational wave of 2/100 Hz; the frequency of acupuncture was mainly performed once per day lasting for more than 2 weeks; the mainly selected acupoints were Huantiao (GB30), Zusanli (ST36), and Yanglingquan (GB34); and the approaches of assessment were contained with behavioral, functional, morphological, histological, cellular, and molecular measurements.
The results indicated that the experimental researches of SNI with acupuncture has made marked progress in recent years, which may provide important clues for further investigating the underlying mechanisms of acupuncture for the treatment of SNI in the future.
收集并总结近十年针刺治疗坐骨神经损伤（SNI）的实验研究相关文献，为今后针刺有效治疗SNI提供指导。
检索2009年至2020年中国知网（CNKI）、万方数据知识服务平台、维普资讯中文期刊服务平台及PubMed等中英文数据库，检索词为“针灸或针刺或电针或头皮针或腕踝针或穴位注射或耳针”以及“坐骨神经或坐骨神经损伤或坐骨损伤或SNI”。收集的数据主要从SNI动物模型、干预类型、穴位选择、疗程及频率、评估方法等方面进行评价。
本分析共纳入89项研究。其中，最常用的SNI动物模型是通过大鼠夹伤或横断损伤制作；最常用的干预方法是2/100Hz疏密波电针；针刺频率主要为每天1次，持续2周以上；主要选取的穴位为环跳（GB30）、足三里（ST36）、阳陵泉（GB34）；评估方法包括行为学、功能学、形态学、组织学、细胞及分子水平的检测。
结果表明，近年来针刺治疗SNI的实验研究取得了显著进展，这可能为今后进一步研究针刺治疗SNI的潜在机制提供重要线索。
