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乳腺癌早期皮肤粘连的推压征

The Pushing Sign for Early Skin Tethering in Breast Cancer.

作者信息

Naraynsingh Vijay, Jarvis Johnathan K, Milne David M, Cawich Shamir O, Harnanan Dave, Singh Yardesh, Islam Shariful

机构信息

Clinical Surgical Sciences, University of the West Indies, St. Augustine, TTO.

Surgery, Medical Associates Hospital, St. Joseph, TTO.

出版信息

Cureus. 2021 Dec 16;13(12):e20471. doi: 10.7759/cureus.20471. eCollection 2021 Dec.

DOI:10.7759/cureus.20471
PMID:34976543
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8682950/
Abstract

Skin tethering (ST) is regarded as a classical clinical feature of breast cancer. In many cases, ST is not evident on inspection, with the arm raised and skin pinching over the lump. We have observed that pushing the lump in one or another direction may elicit skin dimpling that was not otherwise evident. In these cases, there is normal fat, grossly and histologically, between the tumor and the skin. Thus, the dimpling is not due to cutaneous infiltration. We believe that it is caused by tumor involvement of the ligaments of Cooper and present suggestions as to why it might be so. It may be that this is very early involvement of these ligaments, long before ST becomes very obvious. We report our experience with six such cases.

摘要

皮肤粘连(ST)被视为乳腺癌的典型临床特征。在许多情况下,当手臂抬起并在肿块上方捏皮肤时,ST在检查中并不明显。我们观察到,将肿块向一个或另一个方向推动可能会引发原本不明显的皮肤凹陷。在这些病例中,肿瘤与皮肤之间在大体和组织学上均有正常脂肪。因此,这种凹陷并非由皮肤浸润引起。我们认为它是由库珀韧带受肿瘤累及所致,并就其原因提出了相关建议。可能这是这些韧带的非常早期的累及,远在ST变得非常明显之前。我们报告我们在六例此类病例中的经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/6d6b7d79f0ed/cureus-0013-00000020471-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/5f303ecdd467/cureus-0013-00000020471-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/5f56303d84ca/cureus-0013-00000020471-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/f55259370f10/cureus-0013-00000020471-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/8765892a5959/cureus-0013-00000020471-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/9a1132a2e7ed/cureus-0013-00000020471-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/a35425e18055/cureus-0013-00000020471-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/1ba89da54b0e/cureus-0013-00000020471-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/0dfd4e7e3019/cureus-0013-00000020471-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/21d542199630/cureus-0013-00000020471-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/6d6b7d79f0ed/cureus-0013-00000020471-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/5f303ecdd467/cureus-0013-00000020471-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/5f56303d84ca/cureus-0013-00000020471-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/f55259370f10/cureus-0013-00000020471-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/8765892a5959/cureus-0013-00000020471-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/9a1132a2e7ed/cureus-0013-00000020471-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/a35425e18055/cureus-0013-00000020471-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/1ba89da54b0e/cureus-0013-00000020471-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/0dfd4e7e3019/cureus-0013-00000020471-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/21d542199630/cureus-0013-00000020471-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/482b/8682950/6d6b7d79f0ed/cureus-0013-00000020471-i10.jpg

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本文引用的文献

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Impact of mammographic screening on the detection of good and poor prognosis breast cancers.乳腺筛查对良、预后差乳腺癌检出的影响。
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Identifying suspected breast cancer: development and validation of a clinical prediction rule.鉴别疑似乳腺癌:临床预测规则的制定与验证。
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