Smith Brittany T, Brumage Michael R, Zullig Keith J, Claydon Elizabeth A, Smith Megan L, Kristjansson Alfgeir L
Department of Social and Behavioral Sciences West Virginia University School of Public Health, 64 Medical Center Drive P.O. Box 9190, Morgantown, WV 26506-9190, United States.
Post-Deployment Health Services, Veterans Health Administration, Washington, DC, United States.
Prev Med Rep. 2021 Sep 28;24:101571. doi: 10.1016/j.pmedr.2021.101571. eCollection 2021 Dec.
Women with substance use disorder (SUD) often have experienced adverse childhood experiences (ACEs). The intergenerational nature of ACEs also put their children at risk for experiencing ACEs. However, no research has explored the prevalence of ACEs in children whose mothers have SUD. This study assessed ACE scores in mothers with SUD and their children and compared them with non-SUD participants. Females with SUD were recruited from a treatment center (n = 50) and compared to females without SUD from the same area (n = 50). The ACE scores of the participants and their children were measured as well as sociodemographic variables. ANOVA and Fisher's Exact tests were used to examine univariate differences. Multivariate regression models assessed the difference in ACE scores between the groups and their children and the relationship between maternal and child ACE scores while including sociodemographic confounders. The mean ACE score was significantly higher in SUD participants (4.9, = 2.9) when compared to non-SUD participants (1.9, = 2.0) after controlling for sociodemographic variables (p < .01). Children of treatment participants also had significantly higher mean ACE scores (3.9, = 2.3) than children of comparison participants (1.3, = 2.0, p < .01). Maternal ACE score was positively related to children's ACE score after controlling for sociodemographic variables. Given the intergenerational nature of ACEs and their high burden in both mothers and children in substance use treatment, these preliminary findings suggest that mother-child trauma-informed interventions may be appropriate for this population.
患有物质使用障碍（SUD）的女性往往有过不良童年经历（ACEs）。ACEs的代际性质也使她们的孩子有经历ACEs的风险。然而，尚无研究探讨母亲患有SUD的儿童中ACEs的患病率。本研究评估了患有SUD的母亲及其子女的ACEs得分，并将其与非SUD参与者进行比较。从一个治疗中心招募了患有SUD的女性（n = 50），并与来自同一地区的无SUD女性（n = 50）进行比较。测量了参与者及其子女的ACEs得分以及社会人口统计学变量。采用方差分析和费舍尔精确检验来检验单变量差异。多元回归模型评估了两组及其子女在ACEs得分上的差异以及母婴ACEs得分之间的关系，同时纳入了社会人口统计学混杂因素。在控制社会人口统计学变量后，SUD参与者的平均ACE得分（4.9，标准差 = 2.9）显著高于非SUD参与者（1.9，标准差 = 2.0）（p <.01）。治疗参与者的子女的平均ACE得分（3.9，标准差 = 2.3）也显著高于对照参与者的子女（1.3，标准差 = 2.0，p <.01）。在控制社会人口统计学变量后，母亲的ACE得分与子女的ACE得分呈正相关。鉴于ACEs的代际性质及其在物质使用治疗的母亲和儿童中的高负担，这些初步研究结果表明，母婴创伤知情干预可能适用于这一人群。
